Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622146 | 1.00 | EPHX1 (0.35) | EPHX1ALDH1A1CYP3A4NPC1RAB9A | |
| SCHEMBL2192326 | 1.00 | EPHX1 (0.35) | EPHX1ALDH1A1CYP3A4NPC1RAB9A | |
| SCHEMBL7073146 | 1.00 | EPHX1 (0.35) | EPHX1ALDH1A1CYP3A4NPC1RAB9A | |
| SCHEMBL9622157 | 0.96 | TSHR (0.35) | EPHX1ALDH1A1CYP3A4NPC1RAB9A | |
| SCHEMBL9622668 | 0.89 | — | — | |
| SCHEMBL9622195 | 0.81 | — | — | |
| SCHEMBL6114649 | 0.79 | HDAC8 (0.33) | EPHX1ALDH1A1CES2CES1TSHR | |
| SCHEMBL9622434 | 0.79 | CES2 (0.33) | EPHX1ALDH1A1CES2CES1TSHR | |
| Cyclohexylsilanetriol SCHEMBL78580 | 0.79 | CES2 (0.33) | EPHX1ALDH1A1CES2CES1TSHR | |
| SCHEMBL9622673 | 0.79 | CES2 (0.33) | EPHX1ALDH1A1CES2CES1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106959-A | Intermediates for ceramics, gels, films, optical fibers, polymerization catalysts and silicone curing agents | RHONE-POULENC, INC. (US) | 1992-04-21 | — | — | US | disclosed |
| US-5099006-A | ompounds for use in paints, for waterproofing, as adhesion promoters, mordants, sizing agents and intermediates | RHONE-POULENC INC. (US) | 1992-03-24 | — | — | US | disclosed |
| US-5017694-A | With silanol-type compounds | RHONE-POULENC, INC. (US) | 1991-05-21 | — | — | US | disclosed |
| US-5017695-A | With cerium ammonium nitrate and silanol-type compound | RHONE-POULENC, INC. (US) | 1991-05-21 | — | — | US | disclosed |
| EP-0319383-A2 | Process for the fabrication of cerium hydrocarbonsilyloxides by transetherification of cerium alkoxides | RHONE-POULENC CHIMIE (FR) | 1989-06-07 | — | — | EP | disclosed |
| EP-0319384-A2 | Cerium hydrocarbonsilyloxydes and process for their manufacture | RHONE-POULENC CHIMIE (FR) | 1989-06-07 | — | — | EP | disclosed |