SCHEMBL9622157

SCHEMBL9622157

O[Si](O)(C1CCCC1)C1CCCC1

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
ALDH1A1 P00352 3/20 0.31
EPHX1 P07099 5/20 0.30
SMN1; SMN2 Q16637 3/20 0.30
CYP3A4 P08684 2/20 0.30
NPC1 O15118 2/20 0.30
RAB9A P51151 2/20 0.30
TP53 P04637 1/20 0.30
MAPT P10636 1/20 0.30
KDM4E B2RXH2 1/20 0.30
EPHX2 P34913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9622173 0.96 EPHX1 (0.35) TSHRALDH1A1EPHX1SMN1; SMN2CYP3A4
SCHEMBL9622146 0.96 EPHX1 (0.35) TSHRALDH1A1EPHX1SMN1; SMN2CYP3A4
SCHEMBL2192326 0.96 EPHX1 (0.35) TSHRALDH1A1EPHX1SMN1; SMN2CYP3A4
SCHEMBL7073146 0.96 EPHX1 (0.35) TSHRALDH1A1EPHX1SMN1; SMN2CYP3A4
SCHEMBL9622668 0.92
SCHEMBL9622195 0.84
SCHEMBL5576040 0.77 TSHR (0.35) TSHRALDH1A1
SCHEMBL78792 0.77
SCHEMBL4254290 0.77 TSHR (0.35) TSHRALDH1A1
SCHEMBL9622673 0.74 CES2 (0.33) TSHRALDH1A1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116606541-B High-strength dirt-resistant TPU material and preparation method thereof 美瑞新材料股份有限公司 2024-10-18 CN claimed
CN-116606541-A High-strength dirt-resistant TPU material and preparation method thereof 美瑞新材料股份有限公司 2023-08-18 CN claimed
US-12559594-B2 Curable composition, cured product and covered substrate SHIN-ETSU CHEMICAL CO., LTD. (JP) 2026-02-24 US disclosed
US-20250313752-A1 METHOD FOR PRODUCING AQUEOUS SOLUTION OF PURIFIED AMINOSILANOL COMPOUND AND AMINOSILOXANE COMPOUND, AND COMPOSITION FOR ETCHING SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-10-09 US disclosed
EP-4527841-A1 METHOD FOR PRODUCING AQUEOUS SOLUTION OF PURIFIED AMINOSILANOL COMPOUND AND AMINOSILOXANE COMPOUND, AND COMPOSITION FOR ETCHING SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-03-26 EP disclosed
US-20250043080-A1 METHOD FOR PRODUCING ALKOXYSILYL ALKYLAMINOPROPYL-MODIFIED POLYSILOXANE COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-02-06 US disclosed
CN-116606541-B High-strength dirt-resistant TPU material and preparation method thereof 美瑞新材料股份有限公司 2024-10-18 CN disclosed
EP-4410796-A1 METHOD FOR PRODUCING ALKOXYSILYL ALKYLAMINOPROPYL-MODIFIED POLYSILOXANE COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-08-07 EP disclosed
EP-4159794-B1 CURABLE COMPOSITION, CURED PRODUCT AND COVERED SUBSTRATE SHINETSU CHEMICAL CO (JP) 2024-03-06 EP disclosed
WO-2023223803-A1 METHOD FOR PRODUCING AQUEOUS SOLUTION OF PURIFIED AMINOSILANOL COMPOUND AND AMINOSILOXANE COMPOUND, AND COMPOSITION FOR ETCHING 信越化学工業株式会社 2023-11-23 WO disclosed
CN-116606541-A High-strength dirt-resistant TPU material and preparation method thereof 美瑞新材料股份有限公司 2023-08-18 CN disclosed
EP-4159794-A1 CURABLE COMPOSITION, CURED PRODUCT AND COVERED SUBSTRATE Shin-Etsu Chemical Co., Ltd. (JP) 2023-04-05 EP disclosed
EP-2805999-A1 Photosensitive Alkali-Soluble Silicone Resin Composition Asahi Kasei E-materials Corporation (JP) 2014-11-26 EP disclosed
US-20140193632-A1 PHOTOSENSITIVE ALKALI-SOLUBLE SILICONE RESIN COMPOSITION ASAHI KASEI E-MATERIALS CORPORATION (JP) 2014-07-10 US disclosed
EP-2752712-A1 PHOTOSENSITIVE ALKALI-SOLUBLE SILICONE RESIN COMPOSITION Asahi Kasei E-Materials Corporation (JP) 2014-07-09 EP disclosed
US-5106959-A Intermediates for ceramics, gels, films, optical fibers, polymerization catalysts and silicone curing agents RHONE-POULENC, INC. (US) 1992-04-21 US disclosed
US-5099006-A ompounds for use in paints, for waterproofing, as adhesion promoters, mordants, sizing agents and intermediates RHONE-POULENC INC. (US) 1992-03-24 US disclosed
US-5017695-A With cerium ammonium nitrate and silanol-type compound RHONE-POULENC, INC. (US) 1991-05-21 US disclosed
US-5017694-A With silanol-type compounds RHONE-POULENC, INC. (US) 1991-05-21 US disclosed
EP-0324671-A2 Alkoxy-type derivatives of trivalent metals of group 3b, and their preparation RHONE-POULENC CHIMIE (FR) 1989-07-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559594-B2 Curable composition, cured product and covered substrate H1-0, H1-4, H1-2 TSHR 4357/4885ALDH1A1 1264/4885EPHX1 2794/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.