Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.48 |
| ▸ | CDC25B | P30305 | 4/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 2/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | FABP3 | P05413 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21880321 | 0.83 | PTPN1 (0.60) | PTPN1ACE2CDC25BHSD17B10NR4A1 | |
| SCHEMBL6370424 | 0.82 | ACE2 (0.48) | ACE2RXRARXRBRXRGFABP3 | |
| SCHEMBL9622332 | 0.81 | FABP3 (0.41) | ACE2CDC25BCDC25AHSD17B10RXRA | |
| SCHEMBL8458838 | 0.79 | RXRA (0.56) | ACE2RXRARXRBRXRGALDH1A1 | |
| SCHEMBL6560220 | 0.77 | FABP3 (0.50) | ACE2CDC25BCDC25AHSD17B10SORT1 | |
| SCHEMBL28355059 | 0.77 | BCL2 (0.58) | HSD17B10RXRAALDH1A1FABP3FABP4 | |
| SCHEMBL3307626 | 0.75 | FABP3 (0.57) | ACE2HSD17B10RXRARXRBRXRG | |
| SCHEMBL29404396 | 0.73 | PTPN1 (1.00) | PTPN1ACE2CDC25BHSD17B10NR4A1 | |
| SCHEMBL27904823 | 0.73 | FABP3 (0.55) | ACE2HSD17B10RXRARXRBRXRG | |
| SCHEMBL70015 | 0.73 | PTPN1 (1.00) | PTPN1ACE2CDC25BHSD17B10NR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023363-A | Antiinflammatory agent, antiallergens, skin disorders, vision defects | L'OREAL (FR) | 1991-06-11 | — | — | US | claimed |
| US-5093516-A | AROMATIC COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND THEIR USE IN HUMAN AND VETERINARY MEDICINE AND FOR COSMETIC COMPOSITIONS | L'OREAL (FR) | 1992-03-03 | — | — | US | disclosed |
| US-5023363-A | Antiinflammatory agent, antiallergens, skin disorders, vision defects | L'OREAL (FR) | 1991-06-11 | — | — | US | disclosed |