Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | EIF4A3 | P38919 | 2/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.34 |
| ▸ | CDC25A | P30304 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6370424 | 0.82 | ACE2 (0.48) | FABP3FABP4ACE2RXRAEIF4A3 | |
| SCHEMBL9622174 | 0.81 | PTPN1 (0.56) | FABP3FABP4ACE2ALDH1A1RXRA | |
| SCHEMBL8458838 | 0.77 | RXRA (0.56) | FABP3FABP4ACE2ALDH1A1RXRA | |
| SCHEMBL28065832 | 0.76 | EIF4A3 (0.42) | FABP3FABP4EIF4A3DHODHPDE10A | |
| SCHEMBL11591905 | 0.75 | PTPN1 (0.50) | ALDH1A1GRM1HSD17B10MEN1CYP1A2 | |
| SCHEMBL8707349 | 0.74 | ALDH1A1 (0.45) | ALDH1A1HSD17B10MEN1CYP1A2KMT2A | |
| SCHEMBL23909524 | 0.74 | ALDH1A1 (0.41) | ALDH1A1GRM1HSD17B10MEN1CYP1A2 | |
| SCHEMBL8211200 | 0.74 | FABP3 (0.51) | FABP3FABP4ACE2ALDH1A1EIF4A3 | |
| SCHEMBL28355059 | 0.72 | BCL2 (0.58) | FABP3FABP4ALDH1A1RXRAHSD17B10 | |
| SCHEMBL29386062 | 0.72 | FABP3 (0.48) | FABP3FABP4ACE2ALDH1A1EIF4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023363-A | Antiinflammatory agent, antiallergens, skin disorders, vision defects | L'OREAL (FR) | 1991-06-11 | — | — | US | claimed |
| US-5093516-A | AROMATIC COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND THEIR USE IN HUMAN AND VETERINARY MEDICINE AND FOR COSMETIC COMPOSITIONS | L'OREAL (FR) | 1992-03-03 | — | — | US | disclosed |
| US-5023363-A | Antiinflammatory agent, antiallergens, skin disorders, vision defects | L'OREAL (FR) | 1991-06-11 | — | — | US | disclosed |