Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10885494 | 0.88 | MAPT (0.59) | CYP2C19SMN1; SMN2LMNAHPGDTDP1 | |
| SCHEMBL9621935 | 0.82 | CYP2C19 (0.64) | CYP2C19SMN1; SMN2LMNAHPGDCYP3A4 | |
| SCHEMBL8400817 | 0.79 | CYP2C19 (0.60) | CYP2C19SMN1; SMN2LMNAHPGDKDM4E | |
| SCHEMBL11537189 | 0.78 | CYP2C19 (0.68) | CYP2C19SMN1; SMN2LMNAHPGDCYP3A4 | |
| SCHEMBL5935770 | 0.78 | CYP2C19 (0.68) | CYP2C19SMN1; SMN2LMNAHPGDCYP3A4 | |
| SCHEMBL3859999 | 0.78 | TDP1 (0.61) | SMN1; SMN2HPGDTDP1CYP3A4KMT2A | |
| SCHEMBL44801 | 0.77 | CYP2C19 (1.00) | CYP2C19SMN1; SMN2LMNAHPGDTDP1 | |
| SCHEMBL28667334 | 0.77 | CYP3A4 (0.56) | CYP2C19SMN1; SMN2LMNAHPGDTDP1 | |
| SCHEMBL9775108 | 0.76 | CYP2C19 (0.60) | CYP2C19SMN1; SMN2LMNAHPGDKMT2A | |
| SCHEMBL824471 | 0.75 | ALDH1A1 (0.66) | CYP2C19SMN1; SMN2LMNAHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0307358-B1 | 1,3-DIKETONES CONTAINING ETHERS OR THIOETHERS AND THEIR USE AS STABILISING AGENTS IN CHLORINATED POLYMERS | CIBA-GEIGY AG (CH) | 1992-02-12 | — | — | EP | disclosed |
| US-4992504-A | Heat resistance, photostability | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| EP-0307358-A1 | 1,3-Diketones containing ethers or thioethers and their use as stabilising agents in chlorinated polymers | CIBA-GEIGY AG (CH) | 1989-03-15 | — | — | EP | disclosed |