Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | CASP1 | P29466 | 1/20 | 0.69 |
| ▸ | CASP7 | P55210 | 1/20 | 0.69 |
| ▸ | ABCG2 | Q9UNQ0 | 7/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.65 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.65 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.59 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.59 |
| ▸ | DPP4 | P27487 | 1/20 | 0.58 |
| ▸ | XDH | P47989 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4147955 | 0.87 | ABCG2 (0.67) | KDM4ECYP3A4LMNAMAPTTP53 | |
| SCHEMBL30343500 | 0.86 | ABCG2 (0.77) | KDM4ECYP3A4LMNAMAPTTP53 | |
| SCHEMBL20981375 | 0.86 | ABCG2 (0.77) | KDM4ECYP3A4LMNAMAPTTP53 | |
| SCHEMBL16894641 | 0.84 | ABCG2 (0.69) | KDM4ECYP3A4LMNAMAPTTP53 | |
| SCHEMBL30037114 | 0.82 | ADORA3 (0.79) | KDM4ECYP3A4LMNAMAPTTP53 | |
| SCHEMBL16894653 | 0.82 | ADORA3 (0.79) | KDM4ECYP3A4LMNAMAPTTP53 | |
| SCHEMBL31412250 | 0.81 | KDM4E (1.00) | KDM4ECYP3A4LMNAMAPTTP53 | |
| SCHEMBL3135319 | 0.81 | KDM4E (1.00) | KDM4ECYP3A4LMNAMAPTTP53 | |
| SCHEMBL2629300 | 0.81 | ABCG2 (1.00) | KDM4ECYP3A4LMNAMAPTTP53 | |
| SCHEMBL4147950 | 0.81 | ABCG2 (0.81) | KDM4ECYP3A4LMNAMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128429-A | Low temperature block polymerization without randomization | RAYCHEM LIMITED (GB) | 1992-07-07 | — | — | US | disclosed |
| EP-0154506-B1 | PREPARATION OF ORGANIC POLYMERS | RAYCHEM LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| US-4999411-A | Polythioethers, polythiocarbonates, polythioamides, polythioimides | RAYCHEM LIMITED (GB) | 1991-03-12 | — | — | US | disclosed |
| US-4960835-A | ENGINEERING THERMOPLASTICS | RAYCHEM LIMITED (GB) | 1990-10-02 | — | — | US | disclosed |
| US-4845179-A | CONDENSATION POLYMERIZATION | RAYCHEM LIMITED (GB) | 1989-07-04 | — | — | US | disclosed |
| EP-0154506-A2 | Preparation of organic polymers | RAYCHEM LIMITED (GB) | 1985-09-11 | — | — | EP | disclosed |