Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | NT5E | P21589 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH3A1 | P30838 | 4/20 | 0.48 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10706642 | 0.91 | TDP1 (0.59) | MAPTTDP1POLBNT5EMAPK1 | |
| SCHEMBL11226639 | 0.91 | MAPT (0.60) | MAPTTDP1POLBMEN1KMT2A | |
| SCHEMBL10628214 | 0.86 | MAPT (0.54) | MAPTTDP1POLBNT5EMAPK1 | |
| SCHEMBL3240949 | 0.84 | MAPT (0.66) | MAPTTDP1POLBNT5EMAPK1 | |
| SCHEMBL10531845 | 0.82 | ALDH3A1 (0.55) | MAPTTDP1POLBMEN1KMT2A | |
| SCHEMBL9817053 | 0.81 | MAPT (0.74) | MAPTTDP1POLBMAPK1MEN1 | |
| SCHEMBL10721756 | 0.81 | ALDH1A1 (0.56) | MAPTTDP1POLBNT5EMAPK1 | |
| SCHEMBL11439586 | 0.81 | NT5E (0.65) | MAPTTDP1POLBNT5EMAPK1 | |
| SCHEMBL9356739 | 0.80 | ALDH1A1 (0.74) | MAPTTDP1POLBNT5EMAPK1 | |
| SCHEMBL7829819 | 0.80 | MAPT (0.65) | MAPTTDP1POLBNT5EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4859206-A | Hair dye preparations containing nitrodiphenylamine derivative | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1989-08-22 | — | — | US | claimed |
| EP-0280187-B1 | HAIR DYEING COMPOSITIONS WITH DIRECT-DYEING NITRO-DIPHENYL AMINE DERIVATIVES | Henkel Kommanditgesellschaft auf Aktien (DE) | 1992-01-02 | — | — | EP | disclosed |
| US-4859206-A | Hair dye preparations containing nitrodiphenylamine derivative | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1989-08-22 | — | — | US | disclosed |