Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 4/20 | 0.44 |
| ▸ | RXRB | P28702 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622587 | 0.88 | SRD5A2 (0.49) | RXRARXRBMEN1KMT2ACYP26A1 | |
| SCHEMBL420844 | 0.86 | MEN1 (0.48) | MEN1KMT2ACYP26A1CYP3A4CYP26B1 | |
| Hydrochloric Acid SCHEMBL9453210 | 0.85 | MEN1 (0.47) | MEN1KMT2ACYP26A1CYP3A4CYP26B1 | |
| SCHEMBL9622664 | 0.82 | SRD5A2 (0.49) | MEN1KMT2AEPHX2FAAHCNR2 | |
| SCHEMBL23009815 | 0.80 | PKM (0.44) | MEN1KMT2ACYP26A1CYP3A4CYP26B1 | |
| SCHEMBL2387597 | 0.73 | PKM (0.53) | MEN1KMT2AEPHX2FAAHCNR2 | |
| SCHEMBL9622366 | 0.71 | RARB (0.59) | MEN1KMT2ACYP26A1CYP3A4CYP26B1 | |
| SCHEMBL2748283 | 0.71 | EPHX2 (0.60) | MEN1KMT2AEPHX2NPC1RAB9A | |
| SCHEMBL8056506 | 0.71 | MEN1 (0.59) | MEN1KMT2AEPHX2 | |
| SCHEMBL19149733 | 0.71 | HIF1A (0.46) | MEN1KMT2ANR4A2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093516-A | AROMATIC COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND THEIR USE IN HUMAN AND VETERINARY MEDICINE AND FOR COSMETIC COMPOSITIONS | L'OREAL (FR) | 1992-03-03 | — | — | US | disclosed |
| US-5023363-A | Antiinflammatory agent, antiallergens, skin disorders, vision defects | L'OREAL (FR) | 1991-06-11 | — | — | US | disclosed |