Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 8/20 | 0.59 |
| ▸ | RARG | P13631 | 8/20 | 0.59 |
| ▸ | RARA | P10276 | 7/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | PGR | P06401 | 1/20 | 0.58 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.58 |
| ▸ | GOT1 | P17174 | 1/20 | 0.58 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.47 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | IKBKB | O14920 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6364992 | 0.87 | RARA (0.63) | RARBRARGRARAMEN1NR1I2 | |
| SCHEMBL10387338 | 0.84 | RARA (0.57) | RARBRARGRARAMEN1NR1I2 | |
| SCHEMBL8997645 | 0.83 | RARA (0.64) | RARBRARGRARAMEN1NR1I2 | |
| SCHEMBL565789 | 0.81 | RARA (0.77) | RARBRARGRARAMEN1NR1I2 | |
| SCHEMBL1082340 | 0.81 | RARA (0.77) | RARBRARGRARAMEN1NR1I2 | |
| Hydrochloric Acid SCHEMBL9124255 | 0.80 | RARA (0.76) | RARBRARGRARAMEN1NR1I2 | |
| SCHEMBL8872840 | 0.80 | RARA (0.62) | RARBRARGRARAMEN1NR1I2 | |
| SCHEMBL6570369 | 0.80 | S1PR1 (0.71) | RARBRARGRARAMEN1NR1I2 | |
| SCHEMBL8426342 | 0.80 | RARA (0.60) | RARBRARGRARAMEN1NR1I2 | |
| SCHEMBL14027627 | 0.79 | RARB (0.82) | RARBRARGRARAMEN1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093516-A | AROMATIC COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND THEIR USE IN HUMAN AND VETERINARY MEDICINE AND FOR COSMETIC COMPOSITIONS | L'OREAL (FR) | 1992-03-03 | — | — | US | disclosed |
| US-5023363-A | Antiinflammatory agent, antiallergens, skin disorders, vision defects | L'OREAL (FR) | 1991-06-11 | — | — | US | disclosed |