SCHEMBL9622381

SCHEMBL9622381

O=P(O)(Oc1cccc(OP(=O)(O)Oc2cccc(Cl)c2Cl)c1)Oc1cccc(Cl)c1Cl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.43
GAA P10253 1/20 0.43
GPR84 Q9NQS5 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
LMNA P02545 2/20 0.39
SRC P12931 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
MRGPRX4 Q96LA9 1/20 0.38
INPPL1 O15357 2/20 0.37
INPP5A Q14642 2/20 0.37
INPP5B P32019 1/20 0.37
SFN P31947 1/20 0.36
MAPT P10636 1/20 0.36
PTK2B Q14289 1/20 0.36
HTT P42858 1/20 0.35
HCRTR1 O43613 1/20 0.35
NPSR1 Q6W5P4 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11586181 0.90 SRC (0.47) POLBGAAGPR84SMN1; SMN2LMNA
SCHEMBL29114276 0.81 SMN1; SMN2 (0.42) POLBGAASMN1; SMN2LMNACYP1A2
SCHEMBL557291 0.79 INPPL1 (0.59) SMN1; SMN2LMNASRCCYP1A2CYP2D6
SCHEMBL9834120 0.78 LMNA (0.55) POLBGAAGPR84SMN1; SMN2LMNA
SCHEMBL29114274 0.78 SMN1; SMN2 (0.44) POLBGAASMN1; SMN2LMNACYP1A2
SCHEMBL10614735 0.76 SMN1; SMN2 (0.43) POLBGAASMN1; SMN2LMNACYP1A2
SCHEMBL29093880 0.75 CYP1A2 (0.56) SRCCYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL30557968 0.75 SMN1; SMN2 (0.64) POLBGAAGPR84SMN1; SMN2LMNA
SCHEMBL5441328 0.75 SMN1; SMN2 (0.48) POLBGAASMN1; SMN2LMNACYP1A2
SCHEMBL15910518 0.75 SRC (0.61) POLBGPR84SRCCYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5104450-A Films, molding materials; fireproof, plasticizing, stabilization, dimensional stability EASTMAN KODAK COMPANY (US) 1992-04-14 US claimed
WO-1992005219-A1 FORMULATIONS OF CELLULOSE ESTERS WITH ARYLENE-BIS(DIARYL PHOSPHATE)S EASTMAN KODAK COMPANY (US) 1992-04-02 WO claimed