⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5223374 | 0.82 | ALDH1A1 (0.53) | — | |
| SCHEMBL28886 | 0.81 | APP (0.35) | — | |
| SCHEMBL4562089 | 0.79 | GRM5 (0.69) | — | |
| SCHEMBL30469481 | 0.79 | GRM5 (0.69) | — | |
| SCHEMBL30469478 | 0.79 | GRM5 (0.69) | — | |
| Benzoyl Peroxide SCHEMBL864570 | 0.79 | F2 (0.53) | — | |
| Hydrochloric Acid SCHEMBL9124177 | 0.78 | CYP3A4 (0.33) | — | |
| SCHEMBL2321571 | 0.76 | PTPN5 (0.42) | — | |
| SCHEMBL3974204 | 0.76 | KCNH2 (0.46) | — | |
| SCHEMBL138849 | 0.76 | GRM5 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159542-A | Substituted 2, 3-dihydro [1,3] thiazolo [4,5-b ] pyridines, salts thereof and their use as herbicidal agents | 拜耳公司 | 2024-06-07 | — | — | CN | claimed |
| US-20240033318-A1 | PEPTIDYL INHIBITORS OF CALCINEURIN-NFAT INTERACTION | OHIO STATE INNOVATION FOUNDATION | 2024-02-01 | — | — | US | claimed |
| CN-113651863-B | Unsaturated thioglycoside compound and selective synthesis method and application thereof | 华东师范大学 | 2023-11-10 | — | — | CN | claimed |
| US-11576946-B2 | Peptidyl inhibitors of calcineurin-NFAT interaction | OHIO STATE INNOVATION FOUNDATION (US) | 2023-02-14 | — | — | US | claimed |
| CN-114716587-A | Olefin polymerization solid catalyst component containing phenylacetate compounds, and preparation method and application thereof | 中国科学院化学研究所 | 2022-07-08 | — | — | CN | claimed |
| CN-112028813-B | 4-chloro indole compound and preparation method thereof | 平顶山学院 | 2022-03-22 | — | — | CN | claimed |
| CN-113698312-A | Synthetic method of aromatic amide alkene compound | 南京先进生物材料与过程装备研究院有限公司 | 2021-11-26 | — | — | CN | claimed |
| CN-113651863-A | Unsaturated thioglycoside compound and selective synthesis method and application thereof | 华东师范大学 | 2021-11-16 | — | — | CN | claimed |
| US-20210169966-A1 | PEPTIDYL INHIBITORS OF CALCINEURIN-NFAT INTERACTION | OHIO STATE INNOVATION FOUNDATION | 2021-06-10 | — | — | US | claimed |
| EP-3749365-A2 | PEPTIDYL INHIBITORS OF CALCINEURIN-NFAT INTERACTION | Ohio State Innovation Foundation (US) | 2020-12-16 | — | — | EP | claimed |
| WO-1993009117-A1 | IMMUNOSTIMULATING SWAINSONINE ANALOGS | TORONTO RESEARCH CHEMICALS INC. (CA) | 1993-05-13 | — | — | WO | claimed |
| EP-0463162-A1 | PREPARATION OF 5,6,7-TRINOR-4,8-INTER-m-PHENYLENE PGI 2 DERIVATIVES | TORAY INDUSTRIES, INC. (JP) | 1992-01-02 | — | — | EP | claimed |
| EP-0302787-B1 | 2-Methyl(4-piperidinyl)-benzofuro[2,3-c] pyridines, their preparation and therapeutical use | SYNTHELABO (FR) | 1991-10-30 | — | — | EP | claimed |
| US-5049551-A | Antitumor | UBE INDUSTRIES, LTD. (JP) | 1991-09-17 | — | — | US | claimed |
| EP-0400610-A1 | 5-Fluorouracil derivatives | UBE INDUSTRIES, LTD. (JP) | 1990-12-05 | — | — | EP | claimed |
| US-4931449-A | 2-((4-piperidyl)methyl)benzofuro(2,3-C)pyridine derivatives, and their application in therapy | SYNTHELABO (FR) | 1990-06-05 | — | — | US | claimed |
| EP-0343747-A2 | Benzoyl and ketone peroxide compositions | KAYAKU NOURY CORPORATION (JP) | 1989-11-29 | — | — | EP | claimed |
| US-4483861-A | Antihypertensive sulfur-containing compounds | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1984-11-20 | — | — | US | claimed |
| US-4358596-A | Process for the preparation of 1,2,3-thiadiazol-5-yl ureas | SCHERING AG (DE) | 1982-11-09 | — | — | US | claimed |
| US-4301167-A | ANTIINFLAMMATORY AGENTS, ANALGESICS | INSTITUT MERIEUX (FR) | 1981-11-17 | — | — | US | claimed |