Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.53 |
| ▸ | ACE | P12821 | 2/20 | 0.53 |
| ▸ | CPA1 | P15085 | 1/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622537 | 1.00 | MME (0.53) | MMEACECPA1ACE2 | |
| SCHEMBL9622589 | 0.91 | NAALAD2 (0.62) | MMEACE | |
| SCHEMBL9622585 | 0.91 | NAALAD2 (0.62) | MMEACE | |
| SCHEMBL9622475 | 0.81 | FPR2 (0.52) | MMEACECPA1ACE2 | |
| SCHEMBL9622480 | 0.81 | FPR2 (0.52) | MMEACECPA1ACE2 | |
| SCHEMBL30070551 | 0.81 | ACE (0.56) | MMEACECPA1ACE2 | |
| SCHEMBL8388193 | 0.80 | NAALAD2 (0.61) | MME | |
| SCHEMBL28556221 | 0.80 | MME (0.68) | MMEACECPA1ACE2 | |
| SCHEMBL28556220 | 0.80 | MME (0.68) | MMEACECPA1ACE2 | |
| SCHEMBL9622623 | 0.79 | NAALAD2 (0.69) | MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166212-A | Hypotensive agents, analgesics | CIBA-GEIGY CORPORATION (US) | 1992-11-24 | — | — | US | disclosed |
| US-5021430-A | Enkephalinase inhibitors, analgesics, hypotensives | CIBA-GEIGY CORPORATION (US) | 1991-06-04 | — | — | US | disclosed |