Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.62 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.62 |
| ▸ | MME | P08473 | 2/20 | 0.57 |
| ▸ | ACE | P12821 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622585 | 1.00 | NAALAD2 (0.62) | NAALAD2FOLH1MMEACE | |
| SCHEMBL9622541 | 0.91 | MME (0.53) | MMEACE | |
| SCHEMBL9622537 | 0.91 | MME (0.53) | MMEACE | |
| SCHEMBL9622475 | 0.89 | FPR2 (0.52) | NAALAD2FOLH1MMEACE | |
| SCHEMBL9622480 | 0.89 | FPR2 (0.52) | NAALAD2FOLH1MMEACE | |
| SCHEMBL9622621 | 0.88 | NAALAD2 (0.69) | NAALAD2FOLH1MMEACE | |
| SCHEMBL9622623 | 0.88 | NAALAD2 (0.69) | NAALAD2FOLH1MMEACE | |
| SCHEMBL10767779 | 0.84 | ECE1 (0.60) | NAALAD2FOLH1MME | |
| SCHEMBL9622299 | 0.83 | MME (0.80) | NAALAD2FOLH1MMEACE | |
| SCHEMBL9622303 | 0.83 | MME (0.80) | NAALAD2FOLH1MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021430-A | Enkephalinase inhibitors, analgesics, hypotensives | CIBA-GEIGY CORPORATION (US) | 1991-06-04 | — | — | US | claimed |
| EP-0225292-A2 | Certain N-substituted butyramide derivatives | CIBA-GEIGY AG (CH) | 1987-06-10 | — | — | EP | claimed |
| US-5166212-A | Hypotensive agents, analgesics | CIBA-GEIGY CORPORATION (US) | 1992-11-24 | — | — | US | disclosed |
| US-5021430-A | Enkephalinase inhibitors, analgesics, hypotensives | CIBA-GEIGY CORPORATION (US) | 1991-06-04 | — | — | US | disclosed |