Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.65 |
| ▸ | METAP1 | P53582 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622725 | 0.92 | METAP2 (0.68) | METAP2METAP1KDM4EHSD17B10MAPT | |
| SCHEMBL229709 | 0.87 | KDM4E (0.68) | METAP2METAP1KDM4EHSD17B10MAPT | |
| SCHEMBL4185638 | 0.83 | KDM4E (0.61) | METAP2METAP1KDM4EHSD17B10MAPT | |
| SCHEMBL13668122 | 0.83 | KDM4E (0.61) | METAP2METAP1KDM4EHSD17B10MAPT | |
| SCHEMBL4190070 | 0.82 | KDM4E (0.60) | METAP2METAP1KDM4EHSD17B10MAPT | |
| SCHEMBL8266375 | 0.82 | KDM4E (0.66) | METAP2METAP1KDM4EHSD17B10MAPT | |
| SCHEMBL4175508 | 0.82 | KDM4E (0.60) | METAP2METAP1KDM4EHSD17B10MAPT | |
| SCHEMBL10005374 | 0.82 | TLR8 (0.71) | KDM4EHSD17B10NPSR1MEN1KMT2A | |
| SCHEMBL15796790 | 0.81 | TP53 (0.63) | KDM4EHSD17B10MAPTMEN1KMT2A | |
| SCHEMBL13451647 | 0.81 | KDM4E (0.67) | METAP2METAP1KDM4EHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0206030-B1 | PHOTOCURABLE COMPOSITION | SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-01-02 | — | — | EP | disclosed |
| US-4756994-A | Ethylenically unsaturated monomer, photopolymerizable monomer, polymerization inhibitor, nitrogen-containing compound | SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0206030-A2 | Photocurable composition | SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1986-12-30 | — | — | EP | disclosed |