SCHEMBL229709

SCHEMBL229709

CCn1c(-c2cscn2)nc2ccccc21

nearest known ligand 0.71

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.68
HSD17B10 Q99714 1/20 0.68
METAP2 P50579 1/20 0.68
METAP1 P53582 1/20 0.68
MAPT P10636 3/20 0.67
NPSR1 Q6W5P4 1/20 0.67
MAPK1 P28482 2/20 0.61
MEN1 O00255 4/20 0.58
KMT2A Q03164 4/20 0.58
TSHR P16473 1/20 0.56
ALDH1A1 P00352 2/20 0.56
BRD4 O60885 1/20 0.56
KCNH2 Q12809 1/20 0.56
LMNA P02545 1/20 0.56
HPGD P15428 1/20 0.55
HTT P42858 1/20 0.55
RCE1 Q9Y256 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9622725 0.89 METAP2 (0.68) KDM4EHSD17B10METAP2METAP1MAPT
SCHEMBL9622563 0.87 METAP2 (0.65) KDM4EHSD17B10METAP2METAP1MAPT
SCHEMBL13451647 0.85 KDM4E (0.67) KDM4EHSD17B10METAP2METAP1MAPT
SCHEMBL246445 0.83 MAPT (0.71) KDM4EHSD17B10METAP2METAP1MAPT
SCHEMBL6279601 0.83 KDM4E (0.65) KDM4EHSD17B10METAP2METAP1MAPT
SCHEMBL2610128 0.82 KDM4E (0.67) KDM4EHSD17B10METAP2METAP1MAPT
SCHEMBL21085204 0.82 KDM4E (0.64) KDM4EHSD17B10METAP2METAP1MAPT
SCHEMBL6233509 0.81 METAP2 (1.00) KDM4EHSD17B10METAP2METAP1MAPT
SCHEMBL15849710 0.80 KDM4E (0.74) KDM4EHSD17B10MAPTMAPK1MEN1
SCHEMBL230641 0.79 ALDH1A1 (0.70) KDM4EHSD17B10MAPTNPSR1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9011734-B2 Ligand exchange thermochromic, (LETC), systems PLEOTINT, L.L.C. (US) 2015-04-21 US disclosed
EP-2082005-B9 LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS PLEOTINT LLC (US) 2013-05-22 EP disclosed
US-8431045-B2 Ligand exchange thermochromic systems and high ε ligands for same PLEOTINT, L.L.C. (US) 2013-04-30 US disclosed
US-20120292581-A1 LIGAND EXCHANGE THERMOCHROMIC SYSTEMS AND HIGH E LIGANDS FOR SAME PLEOTINT, LLC (US) 2012-11-22 US disclosed
EP-2082005-B1 LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS PLEOTINT LLC (US) 2012-08-01 EP disclosed
US-8182718-B2 Ligand exchange thermochromic systems and high ε ligands for same PLEOTINT, L.L.C. (US) 2012-05-22 US disclosed
EP-2436750-A2 Ligand exchange thermochromic, (LETC), systems Pleotint, L.L.C. (US) 2012-04-04 EP disclosed
EP-2434000-A2 Ligand exchange thermochromic, (LETC), systems Pleotint, L.L.C. (US) 2012-03-28 EP disclosed
US-20120001134-A1 LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS PLEOTINT, LLC (US) 2012-01-05 US disclosed
US-8018639-B2 Ligand exchange thermochromic, (LETC), systems PLEOTINT, L.L.C. (US) 2011-09-13 US disclosed
US-7538931-B2 Ligand exchange thermochromic systems containing exchange metals PLEOTINT, L.L.C. (US) 2009-05-26 US disclosed
US-7525717-B2 reversible; laminated; transition metal ion coordinated with a high epsilon ligand and a low epsilon ligand; polymer; separator; variable light transmission windows; polyvinyl butyral; nickel or cobalt iodide ligands; diol, triol or polyol ligands PLEOTINT, L.L.C. (US) 2009-04-28 US disclosed
US-20080105851-A1 Exhibiting a reversible change in absorbance of electromagnetic radiation as the temperature of the system is reversibly changed; comprising a transition metal ion and a ligand PLEOTINT, LLC (US) 2008-05-08 US disclosed
US-20080106781-A1 LIGAND EXCHANGE THERMOCHROMIC SYSTEMS CONTAINING EXCHANGE METALS PLEOTINT, LLC (US) 2008-05-08 US disclosed
US-20080100903-A1 MULTI-LAYER LIGAND EXCHANGE THERMOCHROMIC SYSTEMS PLEOTINT, LLC (US) 2008-05-01 US disclosed
US-20080100902-A1 LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS PLEOTINT, LLC (US) 2008-05-01 US disclosed
WO-2008028128-A1 LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS PLEOTINT, L.L.C. (US) 2008-03-06 WO disclosed
EP-0206030-B1 PHOTOCURABLE COMPOSITION SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1992-01-02 EP disclosed
US-4756994-A Ethylenically unsaturated monomer, photopolymerizable monomer, polymerization inhibitor, nitrogen-containing compound SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1988-07-12 US disclosed
EP-0206030-A2 Photocurable composition SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1986-12-30 EP disclosed