Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.60 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KDM5C | P41229 | 1/20 | 0.43 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 4/20 | 0.38 |
| ▸ | CASP2 | P42575 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL960434 | 0.87 | CTSD (0.54) | CTSDPAOXKDM4EKDM5CPHF8 | |
| SCHEMBL960759 | 0.86 | CTSD (0.65) | CTSDPAOXKDM4EKDM5CPHF8 | |
| SCHEMBL20025597 | 0.83 | HSP90AA1 (0.59) | PAOXKDM4EKDM5CPHF8KDM2A | |
| SCHEMBL8592695 | 0.82 | PAOX (0.54) | CTSDPAOXKDM4EALDH1A1HDAC1 | |
| SCHEMBL28288916 | 0.82 | CTSD (0.54) | CTSDPAOXALDH1A1HDAC1HDAC2 | |
| SCHEMBL167313 | 0.81 | — | — | |
| SCHEMBL6465629 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL28775240 | 0.79 | CTSD (0.68) | CTSDKDM4EKDM5CPHF8KDM2A | |
| Hydrochloric Acid SCHEMBL7815066 | 0.79 | — | — | |
| SCHEMBL402128 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2248833-B1 | MODIFIED DIENE RUBBER, METHOD FOR PRODUCING THE SAME, RUBBER COMPOSITION USING THE SAME, AND TIRE | BRIDGESTONE CORP (JP) | 2014-03-26 | — | — | EP | disclosed |
| US-20130289165-A1 | COMPOSITION BASED ON NATURAL RUBBER AND CARBON BLACK COMPRISING A HYDRAZIDE, A HYDRAZONE AND A POLYAMINE | MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) | 2013-10-31 | — | — | US | disclosed |
| EP-2655495-A1 | COMPOSITION BASED ON NATURAL RUBBER AND CARBON BLACK COMPRISING A HYDRAZIDE, A HYDRAZONE AND A POLYAMINE | Compagnie Générale des Etablissements Michelin (FR) | 2013-10-30 | — | — | EP | disclosed |
| US-8389641-B2 | Modified diene rubber, production method thereof, and rubber composition and tire using the rubber | BRIDGESTONE CORPORATION (JP) | 2013-03-05 | — | — | US | disclosed |
| WO-2012084821-A1 | COMPOSITION BASED ON NATURAL RUBBER AND CARBON BLACK COMPRISING A HYDRAZIDE, A HYDRAZONE AND A POLYAMINE | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2012-06-28 | — | — | WO | disclosed |
| US-20110003911-A1 | MODIFIED DIENE RUBBER, PRODUCTION METHOD THEREOF, AND RUBBER COMPOSITION AND TIRE USING THE RUBBER | BRIDGESTONE CORPORATION (JP) | 2011-01-06 | — | — | US | disclosed |
| EP-2248833-A1 | MODIFIED DIENE RUBBER, METHOD FOR PRODUCING THE SAME, RUBBER COMPOSITION USING THE SAME, AND TIRE | Bridgestone Corporation (JP) | 2010-11-10 | — | — | EP | disclosed |
| US-20100249336-A1 | MODIFIED NATURAL RUBBER AND METHOD FOR PRODUCING SAME, AND RUBBER COMPOSITION AND TIRE USING SUCH A MODIFIED NATURAL RUBBER | BRIDGESTONE CORPORATION (JP) | 2010-09-30 | — | — | US | disclosed |
| EP-2206730-A1 | MODIFIED NATURAL RUBBER, PROCESS FOR PRODUCTION OF THE SAME, AND RUBBER COMPOSITION AND TIRE EACH COMPRISING THE SAME | Bridgestone Corporation (JP) | 2010-07-14 | — | — | EP | disclosed |