SCHEMBL960434

SCHEMBL960434

CCNCCCC(=O)NN

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CTSD P07339 1/20 0.54
CYP2C19 P33261 3/20 0.44
MEN1 O00255 1/20 0.44
GLA P06280 1/20 0.44
KMT2A Q03164 1/20 0.44
KDM4E B2RXH2 1/20 0.43
KDM5C P41229 1/20 0.43
PHF8 Q9UPP1 1/20 0.43
KDM2A Q9Y2K7 1/20 0.43
ALDH1A1 P00352 1/20 0.42
CYP1A2 P05177 2/20 0.42
TSHR P16473 1/20 0.42
GAA P10253 1/20 0.40
FAAH O00519 1/20 0.38
KDM1A O60341 5/20 0.37
CYP3A4 P08684 1/20 0.37
SAT1 P21673 2/20 0.36
PAOX Q6QHF9 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL962265 0.87 CTSD (0.60) CTSDCYP2C19KDM4EKDM5CPHF8
SCHEMBL961374 0.86
SCHEMBL6902756 0.80 CYP2C19 (0.46) CYP2C19MEN1GLAKMT2ACYP1A2
SCHEMBL3927721 0.79
SCHEMBL960188 0.77
Alcohol SCHEMBL28214729 0.77 CTSD (0.64) CTSDCYP2C19MEN1KMT2AKDM4E
SCHEMBL167313 0.77
SCHEMBL49856 0.75 ALDH1A1 (0.62) CTSDCYP2C19KDM4EKDM5CPHF8
SCHEMBL28219205 0.75 ALDH1A1 (0.62) CTSDCYP2C19KDM4EKDM5CPHF8
SCHEMBL218953 0.75 KDM4E (0.60) CTSDCYP2C19KDM4EKDM5CPHF8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9575067-B2 Polymeric carriers for immunohistochemistry and in situ hybridization VENTANA MEDICAL SYSTEMS, INC. (US) 2017-02-21 US disclosed
US-20150309039-A1 Polymeric Carriers for Immunohistochemistry and In Situ Hybridization VENTANA MEDICAL SYSTEMS 2015-10-29 US disclosed
US-9103822-B2 Polymeric carriers for immunohistochemistry and in situ hybridization VENTANA MEDICAL SYSTEMS, INC. (US) 2015-08-11 US disclosed
US-9017954-B2 Polymeric carriers for immunohistochemistry and in situ hybridization VENTANA MEDICAL SYSTEMS, INC. (US) 2015-04-28 US disclosed
US-20140243236-A1 POLYMERIC CARRIERS FOR IMMUNOHISTOCHEMISTRY AND IN SITU HYBRIDIZATION VENTANA MEDICAL SYSTEMS, INC. (US) 2014-08-28 US disclosed
EP-2248833-B1 MODIFIED DIENE RUBBER, METHOD FOR PRODUCING THE SAME, RUBBER COMPOSITION USING THE SAME, AND TIRE BRIDGESTONE CORP (JP) 2014-03-26 EP disclosed
US-20130289165-A1 COMPOSITION BASED ON NATURAL RUBBER AND CARBON BLACK COMPRISING A HYDRAZIDE, A HYDRAZONE AND A POLYAMINE MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2013-10-31 US disclosed
EP-2655495-A1 COMPOSITION BASED ON NATURAL RUBBER AND CARBON BLACK COMPRISING A HYDRAZIDE, A HYDRAZONE AND A POLYAMINE Compagnie Générale des Etablissements Michelin (FR) 2013-10-30 EP disclosed
US-20130273565-A1 POLYMERIC CARRIERS FOR IMMUNOHISTOCHEMISTRY AND IN SITU HYBRIDIZATION VENTANA MEDICAL SYSTEMS, INC. (US) 2013-10-17 US disclosed
US-8486620-B2 Polymeric carriers for immunohistochemistry and in situ hybridization VENTANA MEDICAL SYSTEMS, INC. (US) 2013-07-16 US disclosed
WO-2012084821-A1 COMPOSITION BASED ON NATURAL RUBBER AND CARBON BLACK COMPRISING A HYDRAZIDE, A HYDRAZONE AND A POLYAMINE COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2012-06-28 WO disclosed
US-20110244545-A1 Polymeric carriers for immunohistochemistry and in situ hybridization VENTANA MEDICAL SYSTEMS, INC. 2011-10-06 US disclosed
US-20110245098-A1 Polymeric carriers for immunohistochemistry and in situ hybridization VENTANA MEDICAL SYSTEMS, INC. 2011-10-06 US disclosed
US-20110244544-A1 Polymeric carriers for immunohistochemistry and in situ hybridization VENTANA MEDICAL SYSTEMS, INC. 2011-10-06 US disclosed
US-7985557-B2 Polymeric carriers for immunohistochemistry and in situ hybridization VENTANA MEDICAL SYSTEMS, INC. (US) 2011-07-26 US disclosed
US-20110003911-A1 MODIFIED DIENE RUBBER, PRODUCTION METHOD THEREOF, AND RUBBER COMPOSITION AND TIRE USING THE RUBBER BRIDGESTONE CORPORATION (JP) 2011-01-06 US disclosed
EP-2248833-A1 MODIFIED DIENE RUBBER, METHOD FOR PRODUCING THE SAME, RUBBER COMPOSITION USING THE SAME, AND TIRE Bridgestone Corporation (JP) 2010-11-10 EP disclosed
US-20100249336-A1 MODIFIED NATURAL RUBBER AND METHOD FOR PRODUCING SAME, AND RUBBER COMPOSITION AND TIRE USING SUCH A MODIFIED NATURAL RUBBER BRIDGESTONE CORPORATION (JP) 2010-09-30 US disclosed
EP-2206730-A1 MODIFIED NATURAL RUBBER, PROCESS FOR PRODUCTION OF THE SAME, AND RUBBER COMPOSITION AND TIRE EACH COMPRISING THE SAME Bridgestone Corporation (JP) 2010-07-14 EP disclosed
US-20080305497-A1 Polymeric carriers for immunohistochemistry and in situ hybridization VENTANA MEDICAL SYSTEMS, INC. 2008-12-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110244545-A1 Polymeric carriers for immunohistochemistry and in situ hybridization FCGR2A, CD68, CA14 CTSD 3041/4885CYP2C19 3507/4885MEN1 4252/4885
US-20150309039-A1 Polymeric Carriers for Immunohistochemistry and In Situ Hybridization FCGR2A, CD68, CA14 CTSD 3041/4885CYP2C19 3507/4885MEN1 4252/4885
US-20140243236-A1 POLYMERIC CARRIERS FOR IMMUNOHISTOCHEMISTRY AND IN SITU HYBRIDIZATION FCGR2A, CD68, CA14 CTSD 3041/4885CYP2C19 3507/4885MEN1 4252/4885
US-20080305497-A1 Polymeric carriers for immunohistochemistry and in situ hybridization FCGR2A, CD68, CA14 CTSD 3041/4885CYP2C19 3507/4885MEN1 4252/4885
US-20110244544-A1 Polymeric carriers for immunohistochemistry and in situ hybridization FCGR2A, CD68, CA14 CTSD 3041/4885CYP2C19 3507/4885MEN1 4252/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.