Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | CA2 | P00918 | 5/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10382537 | 0.98 | ALDH1A1 (0.54) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL9622650 | 0.86 | ALDH1A1 (0.56) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL9622612 | 0.86 | ALDH1A1 (0.56) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL1494204 | 0.84 | ALDH1A1 (0.54) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL31421934 | 0.81 | ALDH1A1 (0.54) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL2018750 | 0.80 | ALDH1A1 (0.50) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL9703821 | 0.80 | ALDH1A1 (0.54) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL10636470 | 0.78 | ALDH1A1 (0.52) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL2686734 | 0.76 | ALDH1A1 (0.50) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL132156 | 0.76 | ALDH1A1 (0.50) | ALDH1A1TDP1CYP3A4TSHRCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106959-A | Intermediates for ceramics, gels, films, optical fibers, polymerization catalysts and silicone curing agents | RHONE-POULENC, INC. (US) | 1992-04-21 | — | — | US | disclosed |
| US-5017694-A | With silanol-type compounds | RHONE-POULENC, INC. (US) | 1991-05-21 | — | — | US | disclosed |
| US-5017695-A | With cerium ammonium nitrate and silanol-type compound | RHONE-POULENC, INC. (US) | 1991-05-21 | — | — | US | disclosed |