SCHEMBL9622773

SCHEMBL9622773

CCCCC(CC)Cc1c(C(=O)O)cc(C(=O)O)c(C(=O)O)c1CC(CC)CCCC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.43
CA2 P00918 4/20 0.43
CYP3A4 P08684 3/20 0.43
TSHR P16473 4/20 0.41
MAPK1 P28482 4/20 0.41
LMNA P02545 3/20 0.39
PRSS1 P07477 1/20 0.38
PRSS2 P07478 1/20 0.38
PRSS3 P35030 1/20 0.38
ATM Q13315 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
HSD17B10 Q99714 1/20 0.36
GLA P06280 1/20 0.36
HTT P42858 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
BCL2L1 Q07817 1/20 0.35
PPARA Q07869 1/20 0.35
HDAC3 O15379 1/20 0.34
HDAC4 P56524 1/20 0.34
HDAC1 Q13547 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20920808 0.94 CA2 (0.41) ALDH1A1CA2CYP3A4TSHRMAPK1
SCHEMBL14989115 0.91 CA2 (0.41) ALDH1A1CA2CYP3A4TSHRMAPK1
SCHEMBL8506941 0.89 ALDH1A1 (0.41) ALDH1A1CA2CYP3A4TSHRMAPK1
SCHEMBL9622770 0.86 ALDH1A1 (0.38) ALDH1A1CA2CYP3A4TSHRMAPK1
SCHEMBL2975546 0.84 ALDH1A1 (0.43) ALDH1A1CA2CYP3A4TSHRMAPK1
SCHEMBL1203004 0.83 KAT8 (0.40) ALDH1A1CA2CYP3A4PRSS1PRSS2
SCHEMBL8944580 0.83 PPARA (0.42) ALDH1A1CA2CYP3A4TSHRMAPK1
SCHEMBL28844950 0.83 BCL2L1 (0.39) ALDH1A1CA2CYP3A4TSHRMAPK1
SCHEMBL14989261 0.83 ALDH1A1 (0.38) ALDH1A1CA2CYP3A4TSHRMAPK1
SCHEMBL621545 0.83 ALDH1A1 (0.48) ALDH1A1CA2CYP3A4TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1567470-B1 HYDROGENATION OF BENZENE POLYCARBOXYLIC ACIDS OR DERIVATIVES THEREOF EXXONMOBIL CHEM PATENTS INC (US) 2013-06-05 EP claimed
EP-0285327-B1 CROSSLINKABLE SILYL POLYMER COMPOSITION BP Chemicals Limited (GB) 1992-04-22 EP claimed
US-4975480-A An addition copolymer of an unsaturated silanol,-diol or -triol, an aromatic ester to prevent premature gelation and a condensation polymerization catalyst BP CHEMICALS LIMITED (GB) 1990-12-04 US claimed
EP-0285327-A2 Crosslinkable silyl polymer composition BP Chemicals Limited (GB) 1988-10-05 EP claimed
EP-0351615-B1 PROCESS FOR THE PREPARATION OF 4-ALKOXY-2-HYDROXYBENZOPHENONE-5-SULFONIC ACIDS BASF Aktiengesellschaft (DE) 1992-10-28 EP disclosed
EP-0351615-A1 Process for the preparation of 4-alkoxy-2-hydroxybenzophenone-5-sulfonic acids BASF Aktiengesellschaft (DE) 1990-01-24 EP disclosed
US-4216337-A FROM POLYCARBOXYLIC ACIDS AND ALCOHOLS FOR USE AS PLASTICIZERS, HEAT TREATMENT THEN ADSORPTION PURIFIES THE PRODUCT MITSUBISHI GAS CHEMICAL CO., INC. (JP) 1980-08-05 US disclosed