Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 8/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7315305 | 0.77 | CHRM2 (0.78) | KDM4ECHRM2OPRK1CYP1A2SLC6A4 | |
| SCHEMBL11845753 | 0.76 | KDM4E (0.60) | KDM4ECHRM2OPRK1CYP1A2SLC6A4 | |
| SCHEMBL9623025 | 0.76 | KDM4E (0.49) | KDM4ECHRM2OPRK1CYP1A2SLC6A4 | |
| SCHEMBL9623023 | 0.76 | KDM4E (0.49) | KDM4ECHRM2OPRK1CYP1A2SLC6A4 | |
| SCHEMBL28298203 | 0.75 | CHRM2 (0.79) | KDM4ECHRM2OPRK1CYP1A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL11849193 | 0.75 | KDM4E (0.59) | KDM4ECHRM2OPRK1CYP1A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL10731346 | 0.75 | CHRM2 (0.74) | KDM4ECHRM2OPRK1CYP1A2SLC6A4 | |
| SCHEMBL18177883 | 0.75 | MEN1 (0.70) | KDM4ECHRM2OPRK1CYP1A2SLC6A4 | |
| SCHEMBL11408767 | 0.74 | HTR1A (0.61) | KDM4ECHRM2OPRK1CYP1A2SLC6A4 | |
| SCHEMBL6162955 | 0.73 | MEN1 (0.59) | KDM4ECHRM2OPRK1CYP1A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5126356-A | Antiischemic agents | ADIR ET COMPAGNIE (FR) | 1992-06-30 | — | — | US | disclosed |