SCHEMBL9622883

SCHEMBL9622883

O=C(O)c1ccc(OC(CCCOc2ccccc2)C(=O)O)c(F)c1

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.51
POLB P06746 1/20 0.48
CASP6 P55212 1/20 0.48
PKM P14618 1/20 0.47
PPARG P37231 8/20 0.46
PPARA Q07869 7/20 0.46
HTT P42858 2/20 0.45
MAPK1 P28482 2/20 0.45
LMNA P02545 1/20 0.45
RAB9A P51151 1/20 0.45
PTGES O14684 1/20 0.44
ALOX5 P09917 1/20 0.44
PARP10 Q53GL7 1/20 0.42
RARB P10826 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TDP1 Q9NUW8 1/20 0.40
PPARD Q03181 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9623914 0.89 PPARG (0.51) FOLH1PPARGPPARAHTTMAPK1
SCHEMBL9623613 0.86 FOLH1 (0.51) FOLH1POLBCASP6PKMPPARG
SCHEMBL9634846 0.81 PPARG (0.64) FOLH1PKMPPARGPPARAMAPK1
SCHEMBL11345159 0.77 PPARG (0.70) FOLH1PPARGPPARAPTGESALOX5
SCHEMBL9623393 0.76 MRGPRX4 (0.46) FOLH1PPARGPPARARAB9APTGES
SCHEMBL9623316 0.75 PPARA (0.46) FOLH1POLBCASP6PPARGPPARA
SCHEMBL9623318 0.75 TDP1 (0.49) FOLH1POLBCASP6PPARGPPARA
SCHEMBL9623931 0.75 MEN1 (0.48) FOLH1POLBPKMPPARGPPARA
SCHEMBL9622934 0.74 PKM (0.60) POLBCASP6PKMHTTMAPK1
SCHEMBL9808855 0.73 RARB (0.58) RARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0212944-B1 MELT-PROCESSABLE AROMATIC COPOLYESTER Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1992-04-08 EP disclosed
US-4746721-A ENGINEERING PLASTICS KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1988-05-24 US disclosed
EP-0212944-A2 Melt-processable aromatic copolyester Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1987-03-04 EP disclosed