SCHEMBL9623914

SCHEMBL9623914

O=C(O)c1ccc(OC(CCCOc2ccccc2F)C(=O)O)c(F)c1

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PPARG P37231 5/20 0.51
PPARA Q07869 5/20 0.51
MRGPRX4 Q96LA9 2/20 0.48
KDM4E B2RXH2 2/20 0.45
FOLH1 Q04609 1/20 0.44
LMNA P02545 1/20 0.44
MAPK1 P28482 1/20 0.44
HTT P42858 1/20 0.44
RAB9A P51151 1/20 0.44
FFAR1 O14842 1/20 0.42
GRM2 Q14416 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
PLA2G2A P14555 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
THRA P10827 1/20 0.40
THRB P10828 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9622883 0.89 FOLH1 (0.51) PPARGPPARAFOLH1LMNAMAPK1
SCHEMBL9623393 0.87 MRGPRX4 (0.46) PPARGPPARAMRGPRX4KDM4EFOLH1
SCHEMBL9623318 0.79 TDP1 (0.49) PPARGPPARAMRGPRX4KDM4EFOLH1
SCHEMBL9623316 0.79 PPARA (0.46) PPARGPPARAKDM4EFOLH1LMNA
SCHEMBL9623931 0.79 MEN1 (0.48) PPARGPPARAMRGPRX4FOLH1LMNA
SCHEMBL9623390 0.77 PPARG (0.43) PPARGPPARAMRGPRX4KDM4ELMNA
SCHEMBL9623616 0.76 RXRA (0.51) PPARGKDM4EFOLH1LMNATDP1
SCHEMBL9623610 0.76 LMNA (0.66) MRGPRX4LMNAMAPK1HTTRAB9A
SCHEMBL9623613 0.75 FOLH1 (0.51) PPARGPPARAFOLH1MAPK1HTT
SCHEMBL27288427 0.75 KDM4E (0.56) PPARGPPARAMRGPRX4KDM4EGRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0212944-B1 MELT-PROCESSABLE AROMATIC COPOLYESTER Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1992-04-08 EP disclosed
US-4746721-A ENGINEERING PLASTICS KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1988-05-24 US disclosed
EP-0212944-A2 Melt-processable aromatic copolyester Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1987-03-04 EP disclosed