Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.49 |
| ▸ | TPMT | P51580 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1749419 | 0.89 | THRA (0.56) | THRATHRBPLA2G2A | |
| SCHEMBL25788081 | 0.86 | PLA2G2A (0.66) | THRATHRBPLA2G2A | |
| SCHEMBL8644661 | 0.86 | PLA2G2A (0.66) | THRATHRBPLA2G2A | |
| SCHEMBL2358713 | 0.86 | PLA2G2A (0.66) | THRATHRBPLA2G2A | |
| SCHEMBL9204687 | 0.83 | THRA (0.42) | PLAUTPMTTHRATHRBMEN1 | |
| SCHEMBL8131511 | 0.82 | PTPN1 (0.44) | PLAUTPMTMEN1KMT2AALDH1A1 | |
| SCHEMBL262782 | 0.80 | SMN1; SMN2 (0.43) | TPMTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL2716010 | 0.80 | TPMT (0.39) | PLAUTPMTTHRATHRBMEN1 | |
| SCHEMBL12377613 | 0.80 | POLB (0.41) | PLAUTPMTTHRATHRBMEN1 | |
| SCHEMBL16645345 | 0.79 | PLA2G2A (0.50) | THRATHRBALDH1A1PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0212944-B1 | MELT-PROCESSABLE AROMATIC COPOLYESTER | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1992-04-08 | — | — | EP | disclosed |
| US-4746721-A | ENGINEERING PLASTICS | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1988-05-24 | — | — | US | disclosed |
| EP-0212944-A2 | Melt-processable aromatic copolyester | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1987-03-04 | — | — | EP | disclosed |