Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 5/20 | 0.45 |
| ▸ | MYLK | Q15746 | 1/20 | 0.44 |
| ▸ | WEE1 | P30291 | 11/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 10/20 | 0.42 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9623319 | 0.91 | ROCK2 (0.48) | ROCK2MYLKWEE1CHEK1TERT | |
| SCHEMBL9622906 | 0.90 | ROCK2 (0.44) | ROCK2MYLKWEE1CHEK1 | |
| SCHEMBL9623320 | 0.90 | CHEK1 (0.44) | ROCK2MYLKWEE1CHEK1TERT | |
| Hydrochloric Acid SCHEMBL9622616 | 0.90 | ROCK2 (0.47) | ROCK2MYLKWEE1CHEK1TERT | |
| Hydrochloric Acid SCHEMBL9623075 | 0.90 | ROCK2 (0.43) | ROCK2MYLKWEE1CHEK1 | |
| Hydrochloric Acid SCHEMBL9622769 | 0.90 | CHEK1 (0.44) | ROCK2MYLKWEE1CHEK1TERT | |
| SCHEMBL9623259 | 0.88 | CHEK1 (0.43) | ROCK2MYLKWEE1CHEK1TERT | |
| SCHEMBL9622489 | 0.87 | MYLK (0.45) | ROCK2MYLKWEE1CHEK1TERT | |
| SCHEMBL9623107 | 0.87 | MYLK (0.46) | ROCK2MYLKWEE1CHEK1TERT | |
| SCHEMBL29351301 | 0.87 | MYLK (0.46) | ROCK2MYLKWEE1CHEK1TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166204-A | ISOINDOLE DERIVATIVES AND SALTS THEREOF AND ANTITUMOR AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1992-11-24 | — | — | US | claimed |