Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 5/20 | 0.49 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | HTR6 | P50406 | 3/20 | 0.49 |
| ▸ | TERT | O14746 | 2/20 | 0.49 |
| ▸ | HEXA | P06865 | 1/20 | 0.48 |
| ▸ | HEXB | P07686 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | HRH1 | P35367 | 3/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9622924 | 0.81 | MEN1 (0.46) | TERTHEXAHEXBALDH1A1KDM4E | |
| SCHEMBL9622936 | 0.79 | TERT (0.52) | MPOHAVCR2DRD2HTR6TERT | |
| Hydrochloric Acid SCHEMBL9622732 | 0.78 | TERT (0.51) | MPOHAVCR2DRD2HTR6TERT | |
| SCHEMBL30839875 | 0.75 | HEXA (0.72) | DRD2HTR6TERTHEXAHEXB | |
| SCHEMBL13590076 | 0.75 | HEXA (0.72) | DRD2HTR6TERTHEXAHEXB | |
| SCHEMBL9623161 | 0.73 | TERT (0.43) | DRD2HTR6TERTHEXAHEXB | |
| SCHEMBL29377476 | 0.73 | CHEK1 (0.50) | MPOHAVCR2DRD2HTR6TERT | |
| Hydrochloric Acid SCHEMBL27677276 | 0.73 | HEXA (0.70) | DRD2HTR6TERTHEXAHEXB | |
| SCHEMBL19651135 | 0.70 | AHR (0.63) | LMNAMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL25834906 | 0.70 | AHR (0.63) | LMNAMAPTALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166204-A | ISOINDOLE DERIVATIVES AND SALTS THEREOF AND ANTITUMOR AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1992-11-24 | — | — | US | disclosed |