Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 2/20 | 0.43 |
| ▸ | HEXA | P06865 | 1/20 | 0.39 |
| ▸ | HEXB | P07686 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622491 | 0.80 | TERT (0.46) | TERTHEXAHEXBSLC6A4HRH1 | |
| SCHEMBL9622996 | 0.73 | MPO (0.49) | TERTHEXAHEXBSLC6A4HRH1 | |
| Hydrochloric Acid SCHEMBL9622924 | 0.68 | MEN1 (0.46) | TERTHEXAHEXBMEN1KMT2A | |
| SCHEMBL438793 | 0.66 | TERT (0.56) | TERTHEXAHEXBSLC6A4HRH1 | |
| SCHEMBL25815092 | 0.65 | KDM4E (0.59) | MAPTTP53MEN1KMT2AKDM4E | |
| SCHEMBL25811214 | 0.64 | TP53 (0.75) | MAPTTP53MEN1KMT2AKDM4E | |
| SCHEMBL17557104 | 0.64 | HEXA (0.61) | TERTHEXAHEXBSLC6A4HRH1 | |
| SCHEMBL9623274 | 0.64 | TERT (0.49) | TERTHEXAHEXBMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL9623400 | 0.63 | TERT (0.48) | TERTHEXAHEXBMAPTMEN1 | |
| SCHEMBL17557141 | 0.63 | FTO (0.57) | TERTHEXAHEXBSLC6A4HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166204-A | ISOINDOLE DERIVATIVES AND SALTS THEREOF AND ANTITUMOR AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1992-11-24 | — | — | US | disclosed |