Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ESRRB | O95718 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29506634 | 1.00 | GRIK1 (0.38) | GRIK1GRIK2SMN1; SMN2CA1CA2 | |
| SCHEMBL16077000 | 1.00 | GRIK1 (0.38) | GRIK1GRIK2SMN1; SMN2CA1CA2 | |
| SCHEMBL9624230 | 0.84 | GRIK1 (0.41) | GRIK1GRIK2SMN1; SMN2CA1CA2 | |
| SCHEMBL19403913 | 0.83 | GRIK1 (0.38) | GRIK1GRIK2HSD17B10CHRM1KDM4E | |
| SCHEMBL9623114 | 0.83 | GRIK1 (0.38) | GRIK1GRIK2HSD17B10CHRM1KDM4E | |
| SCHEMBL10941951 | 0.81 | GRIK1 (0.39) | GRIK1GRIK2SMN1; SMN2CA1CA2 | |
| SCHEMBL16406944 | 0.81 | CTSK (0.38) | GRIK1GRIK2SMN1; SMN2CA1CA2 | |
| SCHEMBL19384549 | 0.81 | CTSK (0.38) | GRIK1GRIK2SMN1; SMN2CA1CA2 | |
| SCHEMBL996344 | 0.81 | CTSK (0.38) | GRIK1GRIK2SMN1; SMN2CA1CA2 | |
| SCHEMBL7111734 | 0.78 | GRIK1 (0.44) | GRIK1GRIK2SMN1; SMN2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109196111-B | Process for producing optically active carboxylic acids, carboxylic acid salts and carboxylic acid derivatives containing triple bonds | 奇诺因药物和化学工厂私人有限公司 | 2022-03-11 | — | — | CN | disclosed |
| US-11008594-B2 | Process for the preparation of triple-bond-containing optically active carboxylic acids, carboxylate salts and carboxylic acid derivatives | CHINOIN PHARMACEUTICAL AND CHEMICAL WORKS PRIVATE COMPANY LTD. (HU) | 2021-05-18 | — | — | US | disclosed |
| US-20200123578-A1 | PROCESS FOR THE PREPARATION OF TRIPLE-BOND-CONTAINING OPTICALLY ACTIVE CARBOXYLIC ACIDS, CARBOXYLATE SALTS AND CARBOXYLIC ACID DERIVATIVES | CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. (HU) | 2020-04-23 | — | — | US | disclosed |
| EP-3433375-B1 | PROCESS FOR THE PREPARATION OF TRIPLE-BOND-CONTAINING OPTICALLY ACTIVE CARBOXYLIC ACIDS, CARBOXYLATE SALTS AND CARBOXYLIC ACID DERIVATIVES | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA ZRT (HU) | 2020-01-29 | — | — | EP | disclosed |
| EP-3433375-B1 | PROCESS FOR THE PREPARATION OF TRIPLE-BOND-CONTAINING OPTICALLY ACTIVE CARBOXYLIC ACIDS, CARBOXYLATE SALTS AND CARBOXYLIC ACID DERIVATIVES | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA ZRT (HU) | 2020-01-29 | — | — | EP | disclosed |
| EP-3433375-A1 | PROCESS FOR THE PREPARATION OF TRIPLE-BOND-CONTAINING OPTICALLY ACTIVE CARBOXYLIC ACIDS, CARBOXYLATE SALTS AND CARBOXYLIC ACID DERIVATIVES | Chinoin Gyógyszer és Vegyészeti Termékek Gyára Zrt. (HU) | 2019-01-30 | — | — | EP | disclosed |
| CN-109196111-A | The method for being used to prepare the optically active carboxylic acid, carboxylate and carboxylic acid derivates that contain three keys | 奇诺因药物和化学工厂私人有限公司 | 2019-01-11 | — | — | CN | disclosed |
| WO-2017162667-A1 | PROCESS FOR THE PREPARATION OF TRIPLE-BOND-CONTAINING OPTICALLY ACTIVE CARBOXYLIC ACIDS, CARBOXYLATE SALTS AND CARBOXYLIC ACID DERIVATIVES | CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. (HU) | 2017-09-28 | — | — | WO | disclosed |
| WO-2017162667-A1 | PROCESS FOR THE PREPARATION OF TRIPLE-BOND-CONTAINING OPTICALLY ACTIVE CARBOXYLIC ACIDS, CARBOXYLATE SALTS AND CARBOXYLIC ACID DERIVATIVES | CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. (HU) | 2017-09-28 | — | — | WO | disclosed |
| EP-0274064-B1 | 2,5,6,7-TETRANOR-18,18,19,19-TETRADEHYDRO-4,8-INTER-M-PHENYLENE PGI2 DERIVATIVES | TORAY INDUSTRIES, INC. (JP) | 1992-03-18 | — | — | EP | disclosed |
| US-4880939-A | ANTISECRETORY AGENTS, HYPOTENSIVES, ANTICOAGULANTS | TORAY INDUSTRIES (JP) | 1989-11-14 | — | — | US | disclosed |
| EP-0274064-A2 | 2,5,6,7-Tetranor-18,18,19,19-tetradehydro-4,8-inter-m-phenylene PGI2 derivatives | TORAY INDUSTRIES, INC. (JP) | 1988-07-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200123578-A1 | PROCESS FOR THE PREPARATION OF TRIPLE-BOND-CONTAINING OPTICALLY ACTIVE CARBOXYLIC ACIDS, CARBOXYLATE SALTS AND CARBOXYLIC ACID DERIVATIVES | ACADM, CES1, ACE | GRIK1 369/4885GRIK2 794/4885SMN1; SMN2 3699/4885 |
| US-11008594-B2 | Process for the preparation of triple-bond-containing optically active carboxylic acids, carboxylate salts and carboxylic acid derivatives | ACADM, CES1, ACE | GRIK1 369/4885GRIK2 794/4885SMN1; SMN2 3699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.