Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 5/20 | 0.31 |
| ▸ | ESRRB | O95718 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 3/20 | 0.31 |
| ▸ | MMP9 | P14780 | 3/20 | 0.31 |
| ▸ | MMP13 | P45452 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16406944 | 1.00 | CTSK (0.38) | CTSKSMN1; SMN2GRIK1GRIK2CA14 | |
| SCHEMBL19384549 | 1.00 | CTSK (0.38) | CTSKSMN1; SMN2GRIK1GRIK2CA14 | |
| SCHEMBL29506634 | 0.81 | GRIK1 (0.38) | SMN1; SMN2GRIK1GRIK2CA14CA12 | |
| SCHEMBL9623059 | 0.81 | GRIK1 (0.38) | SMN1; SMN2GRIK1GRIK2CA14CA12 | |
| SCHEMBL14317200 | 0.81 | ALDH1A1 (0.37) | CTSKGRIK1GRIK2HSD17B10CHRM1 | |
| SCHEMBL16077000 | 0.81 | GRIK1 (0.38) | SMN1; SMN2GRIK1GRIK2CA14CA12 | |
| SCHEMBL9623996 | 0.81 | ALDH1A1 (0.37) | CTSKGRIK1GRIK2HSD17B10CHRM1 | |
| SCHEMBL16080155 | 0.80 | CTSK (0.39) | CTSKSMN1; SMN2GRIK1GRIK2CA14 | |
| SCHEMBL13101794 | 0.79 | SMN1; SMN2 (0.34) | SMN1; SMN2CA14CA12MME | |
| SCHEMBL10129866 | 0.78 | SMN1; SMN2 (0.33) | SMN1; SMN2CA14CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105503595-B | A kind of preparation method of the methyl of R types 2 oneself 4 ynoic acid methyl esters | 上海北卡医药技术有限公司 | 2017-07-07 | — | — | CN | claimed |
| CN-114957326-A | Synthesis method of beraprost sodium phosphine ylide intermediate | 吉尔多肽生物制药(大连市)有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-109196111-B | Process for producing optically active carboxylic acids, carboxylic acid salts and carboxylic acid derivatives containing triple bonds | 奇诺因药物和化学工厂私人有限公司 | 2022-03-11 | — | — | CN | disclosed |
| US-11008594-B2 | Process for the preparation of triple-bond-containing optically active carboxylic acids, carboxylate salts and carboxylic acid derivatives | CHINOIN PHARMACEUTICAL AND CHEMICAL WORKS PRIVATE COMPANY LTD. (HU) | 2021-05-18 | — | — | US | disclosed |
| US-20200123578-A1 | PROCESS FOR THE PREPARATION OF TRIPLE-BOND-CONTAINING OPTICALLY ACTIVE CARBOXYLIC ACIDS, CARBOXYLATE SALTS AND CARBOXYLIC ACID DERIVATIVES | CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. (HU) | 2020-04-23 | — | — | US | disclosed |
| EP-3433375-B1 | PROCESS FOR THE PREPARATION OF TRIPLE-BOND-CONTAINING OPTICALLY ACTIVE CARBOXYLIC ACIDS, CARBOXYLATE SALTS AND CARBOXYLIC ACID DERIVATIVES | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA ZRT (HU) | 2020-01-29 | — | — | EP | disclosed |
| EP-3433375-B1 | PROCESS FOR THE PREPARATION OF TRIPLE-BOND-CONTAINING OPTICALLY ACTIVE CARBOXYLIC ACIDS, CARBOXYLATE SALTS AND CARBOXYLIC ACID DERIVATIVES | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA ZRT (HU) | 2020-01-29 | — | — | EP | disclosed |
| EP-3433375-A1 | PROCESS FOR THE PREPARATION OF TRIPLE-BOND-CONTAINING OPTICALLY ACTIVE CARBOXYLIC ACIDS, CARBOXYLATE SALTS AND CARBOXYLIC ACID DERIVATIVES | Chinoin Gyógyszer és Vegyészeti Termékek Gyára Zrt. (HU) | 2019-01-30 | — | — | EP | disclosed |
| CN-109196111-A | The method for being used to prepare the optically active carboxylic acid, carboxylate and carboxylic acid derivates that contain three keys | 奇诺因药物和化学工厂私人有限公司 | 2019-01-11 | — | — | CN | disclosed |
| WO-2017162667-A1 | PROCESS FOR THE PREPARATION OF TRIPLE-BOND-CONTAINING OPTICALLY ACTIVE CARBOXYLIC ACIDS, CARBOXYLATE SALTS AND CARBOXYLIC ACID DERIVATIVES | CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. (HU) | 2017-09-28 | — | — | WO | disclosed |
| EP-0092352-B1 | 9-SUBSTITUTED CARBACYCLINS | THE UPJOHN COMPANY (US) | 1986-07-02 | — | — | EP | disclosed |
| US-4590297-A | Novel 9-substituted carbacyclin analogs | THE UPJOHN COMPANY (US) | 1986-05-20 | — | — | US | disclosed |
| EP-0087237-B1 | CARBACYCLIN ANALOGUES | THE UPJOHN COMPANY (US) | 1986-05-14 | — | — | EP | disclosed |
| EP-0086612-B1 | 9-SUBSTITUTED CARBACYCLIN ANALOGUES | THE UPJOHN COMPANY (US) | 1986-05-07 | — | — | EP | disclosed |
| US-4533749-A | 9-Substituted carbacyclin analogs | THE UPJOHN COMPANY (US) | 1985-08-06 | — | — | US | disclosed |
| US-4487960-A | 9-Substituted carbacyclin analogs | THE UPJOHN COMPANY (US) | 1984-12-11 | — | — | US | disclosed |
| US-4486598-A | ANTIULCER, ANTICOAGULANT, ANTIASTHMA | THE UPJOHN COMPANY (US) | 1984-12-04 | — | — | US | disclosed |
| EP-0092352-A1 | 9-Substituted carbacyclins | THE UPJOHN COMPANY (US) | 1983-10-26 | — | — | EP | disclosed |
| EP-0087237-A1 | Carbacyclin analogues | THE UPJOHN COMPANY (US) | 1983-08-31 | — | — | EP | disclosed |
| EP-0086612-A1 | 9-Substituted carbacyclin analogues | THE UPJOHN COMPANY (US) | 1983-08-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200123578-A1 | PROCESS FOR THE PREPARATION OF TRIPLE-BOND-CONTAINING OPTICALLY ACTIVE CARBOXYLIC ACIDS, CARBOXYLATE SALTS AND CARBOXYLIC ACID DERIVATIVES | ACADM, CES1, ACE | CTSK 89/4885SMN1; SMN2 3699/4885GRIK1 369/4885 |
| US-11008594-B2 | Process for the preparation of triple-bond-containing optically active carboxylic acids, carboxylate salts and carboxylic acid derivatives | ACADM, CES1, ACE | CTSK 89/4885SMN1; SMN2 3699/4885GRIK1 369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.