Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KIF11 | P52732 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979591 | 0.84 | KDM4E (0.72) | NPC1KMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL9623129 | 0.83 | ALDH1A1 (0.57) | KMT2AKDM4EMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9622456 | 0.83 | KDM4E (0.70) | NPC1KMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL9622760 | 0.82 | ALDH1A1 (0.66) | NPC1KMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL7378899 | 0.79 | GABRA1 (0.74) | NPC1KDM4EMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL24375425 | 0.79 | KMT2A (0.58) | NPC1KMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL3283431 | 0.79 | ALDH1A1 (0.69) | NPC1KMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL9937467 | 0.79 | GAA (0.72) | NPC1KMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL30175047 | 0.79 | ALDH1A1 (0.61) | KMT2AKDM4EALDH1A1MEN1GABRA1 | |
| SCHEMBL5313637 | 0.79 | ALDH1A1 (0.61) | KMT2AKDM4EALDH1A1MEN1GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166204-A | ISOINDOLE DERIVATIVES AND SALTS THEREOF AND ANTITUMOR AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1992-11-24 | — | — | US | disclosed |