Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ENO1 | P06733 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9548001 | 0.80 | — | — | |
| SCHEMBL9624216 | 0.78 | PTPN7 (0.35) | MEN1HPGDBLMKMT2ATDP1 | |
| SCHEMBL9624038 | 0.76 | PTPN7 (0.41) | MEN1HPGDBLMKMT2ATDP1 | |
| SCHEMBL10682474 | 0.73 | LMNA (0.40) | MEN1LMNAHPGDTSHRBLM | |
| SCHEMBL10477516 | 0.70 | TSHR (0.35) | TSHR | |
| SCHEMBL10683719 | 0.69 | FDPS (0.41) | MEN1LMNAHPGDTSHRBLM | |
| SCHEMBL8721557 | 0.69 | LMNA (0.46) | MEN1LMNAHPGDTSHRBLM | |
| SCHEMBL9547937 | 0.69 | MEN1 (0.33) | MEN1LMNAHPGDTSHRBLM | |
| SCHEMBL9090285 | 0.69 | MEN1 (0.33) | MEN1LMNAHPGDTSHRBLM | |
| SCHEMBL10684403 | 0.68 | MEN1 (0.36) | MEN1LMNAHPGDTSHRBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274064-B1 | 2,5,6,7-TETRANOR-18,18,19,19-TETRADEHYDRO-4,8-INTER-M-PHENYLENE PGI2 DERIVATIVES | TORAY INDUSTRIES, INC. (JP) | 1992-03-18 | — | — | EP | disclosed |
| US-4880939-A | ANTISECRETORY AGENTS, HYPOTENSIVES, ANTICOAGULANTS | TORAY INDUSTRIES (JP) | 1989-11-14 | — | — | US | disclosed |
| US-4775692-A | ANTILIPEMIC, ANTICOAGULANT, HYPOTENSIVE, ANTISECRETORY AND ANTIULCER AGENT | TORAY INDUSTRIES, INC. (JP) | 1988-10-04 | — | — | US | disclosed |
| EP-0274064-A2 | 2,5,6,7-Tetranor-18,18,19,19-tetradehydro-4,8-inter-m-phenylene PGI2 derivatives | TORAY INDUSTRIES, INC. (JP) | 1988-07-13 | — | — | EP | disclosed |
| US-4235930-A | INDUCTION OF MENSTRUATION OR ABORTION | SCHERING, A.G. (DE) | 1980-11-25 | — | — | US | disclosed |
| US-4191694-A | HYPOTENSIVE, ANTISECRETORY, ANTIULCER, ANTIARRHYTHMIA AGENTS; ANTICOAGULANTS, DIURETICS | SCHERING AKTIENGESELLSCHAFT (DE) | 1980-03-04 | — | — | US | disclosed |