Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 3/20 | 0.50 |
| ▸ | PREP | P48147 | 2/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL9623008 | 0.93 | HTR4 (0.47) | HTR4PREPCNR2PRMT5WDR77 | |
| Fumaric Acid SCHEMBL9623002 | 0.93 | HTR4 (0.47) | HTR4PREPCNR2PRMT5WDR77 | |
| SCHEMBL9623103 | 0.79 | CHRNA7 (0.54) | CNR2CHRNA7HTR3AKMT2A | |
| SCHEMBL9458315 | 0.78 | PREP (0.48) | HTR4PREPCNR2PRMT5WDR77 | |
| SCHEMBL590971 | 0.77 | PREP (0.49) | HTR4PREPCNR2PRMT5WDR77 | |
| SCHEMBL9622442 | 0.76 | BCHE (0.52) | HTR4HDAC1HDAC2HDAC3KMT2A | |
| SCHEMBL7398258 | 0.75 | KMT2A (0.54) | HTR4PREPPRMT5WDR77CHRNA7 | |
| SCHEMBL9078900 | 0.75 | CNR2 (0.50) | HTR4PREPCNR2PRMT5WDR77 | |
| SCHEMBL10078783 | 0.74 | HTR4 (0.48) | HTR4PREPCNR2PRMT5WDR77 | |
| SCHEMBL8422190 | 0.72 | HTR4 (0.72) | HTR4PREPPRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5137895-A | Antiemetic, anxiolytic, gastric emptying and serotonin modulating activity | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-08-11 | — | — | US | claimed |