SCHEMBL9623231

SCHEMBL9623231

CC(C)Oc1ccccc1N=C=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.47
ALDH1A1 P00352 4/20 0.43
TDP1 Q9NUW8 3/20 0.43
IRAK4 Q9NWZ3 2/20 0.43
HPGD P15428 1/20 0.43
ACHE P22303 1/20 0.41
KDM4E B2RXH2 2/20 0.39
MAPT P10636 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
LMNA P02545 2/20 0.36
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
TRPA1 O75762 1/20 0.34
ADRA2A P08913 1/20 0.34
ADRA2B P18089 1/20 0.34
ADRA2C P18825 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL628189 0.81 CYP3A4 (0.42) CYP3A4ALDH1A1TDP1HPGDKDM4E
SCHEMBL29648867 0.81 CYP3A4 (0.42) CYP3A4ALDH1A1TDP1HPGDKDM4E
SCHEMBL6118482 0.81 ALDH1A1 (0.43) CYP3A4ALDH1A1TDP1IRAK4HPGD
SCHEMBL31540602 0.81 ALDH1A1 (0.43) CYP3A4ALDH1A1TDP1IRAK4HPGD
SCHEMBL15321040 0.80 CYP3A4 (0.46) CYP3A4ALDH1A1TDP1IRAK4HPGD
SCHEMBL77114 0.79 ALDH1A1 (0.61) CYP3A4ALDH1A1TDP1HPGDMAPT
SCHEMBL29471398 0.79 ALDH1A1 (0.61) CYP3A4ALDH1A1TDP1HPGDMAPT
SCHEMBL1356140 0.78 CYP3A4 (0.50) CYP3A4ALDH1A1TDP1HPGDTRPA1
SCHEMBL29369823 0.78 CYP3A4 (0.50) CYP3A4ALDH1A1TDP1HPGDTRPA1
SCHEMBL9622718 0.77 CYP3A4 (0.43) CYP3A4ALDH1A1TDP1HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0271914-B1 POLYESTERAMIDE WITH IMPROVED COMPRESSION SET THE DOW CHEMICAL COMPANY (US) 1992-01-08 EP disclosed
US-4772649-A Polyesteramide and sufficient carbodiimide to impart improved compression set THE DOW CHEMICAL COMPANY (US) 1988-09-20 US disclosed
EP-0271914-A2 Polyesteramide with improved compression set THE DOW CHEMICAL COMPANY (US) 1988-06-22 EP disclosed
US-4174393-A INSECTICIDES DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1979-11-13 US disclosed