SCHEMBL9623262

SCHEMBL9623262

COCn1ccc2cc(OC)ccc21

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 2/20 0.62
MTNR1A P48039 2/20 0.52
MTNR1B P49286 2/20 0.52
KDM4E B2RXH2 1/20 0.50
MEN1 O00255 1/20 0.50
MAPT P10636 1/20 0.50
KMT2A Q03164 1/20 0.50
HTR2A P28223 1/20 0.49
POLB P06746 1/20 0.47
HTR6 P50406 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
PRMT5 O14744 4/20 0.46
ROCK1 Q13464 1/20 0.44
HDAC11 Q96DB2 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
SLC6A2 P23975 1/20 0.44
TUBB1 Q9H4B7 1/20 0.43
CYP1A2 P05177 1/20 0.42
CYP2A6 P11509 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7232114 0.84 HTR2C (0.64) HTR2CMTNR1AMTNR1BKDM4EMEN1
SCHEMBL18857024 0.81 MTNR1A (0.62) HTR2CMTNR1AMTNR1BKDM4EMEN1
SCHEMBL4204521 0.79 MTNR1A (0.60) HTR2CMTNR1AMTNR1BKDM4EMEN1
SCHEMBL7962397 0.79 HTR2C (0.59) HTR2CMTNR1AMTNR1BKDM4EMEN1
SCHEMBL18997057 0.79 HTR2C (0.59) HTR2CMTNR1AMTNR1BKDM4EMEN1
SCHEMBL6803161 0.79 HTR2C (0.63) HTR2CMTNR1AMTNR1BKDM4EMEN1
Dimethylamine SCHEMBL3332584 0.79 MTNR1A (0.60) HTR2CMTNR1AMTNR1BKDM4EMEN1
SCHEMBL3817124 0.79 HTR2C (0.59) HTR2CMTNR1AMTNR1BKDM4EMEN1
SCHEMBL22930056 0.79 HTR2C (0.77) HTR2CMTNR1AMTNR1BKDM4EMEN1
SCHEMBL29162319 0.79 HTR2C (0.59) HTR2CMTNR1AMTNR1BKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4601638-A2 ACETAL, KETAL, AND HEMIAMINAL ANALOGS OF PSILOCIN, PROCESSES FOR THE PREPARATION THEREOF, AND METHODS OF USE ATAI Therapeutics, Inc. (US) 2025-08-20 EP disclosed
WO-2024081962-A2 ACETAL, KETAL, AND HEMIAMINAL ANALOGS OF PSILOCIN, PROCESSES FOR THE PREPARATION THEREOF, AND METHODS OF USE INVYXIS, INC. (US) 2024-04-18 WO disclosed
US-5166204-A ISOINDOLE DERIVATIVES AND SALTS THEREOF AND ANTITUMOR AGENT COMPRISING THE SAME TOYAMA CHEMICAL CO., LTD. (JP) 1992-11-24 US disclosed