Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 2/20 | 0.49 |
| ▸ | HEXA | P06865 | 1/20 | 0.42 |
| ▸ | HEXB | P07686 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | WEE1 | P30291 | 4/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | NEK1 | Q96PY6 | 2/20 | 0.38 |
| ▸ | PLK1 | P53350 | 4/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9623400 | 0.99 | TERT (0.48) | TERTHEXAHEXBSTAT3HIF1A | |
| SCHEMBL9623021 | 0.89 | WEE1 (0.51) | TERTHEXAHEXBSTAT3HIF1A | |
| Hydrochloric Acid SCHEMBL9623357 | 0.88 | WEE1 (0.50) | TERTHEXAHEXBSTAT3HIF1A | |
| SCHEMBL9623078 | 0.84 | TERT (0.47) | TERTHEXAHEXBSTAT3HIF1A | |
| SCHEMBL29351752 | 0.84 | TERT (0.47) | TERTHEXAHEXBSTAT3HIF1A | |
| SCHEMBL9622438 | 0.84 | TERT (0.49) | TERTHEXAHEXBSTAT3HIF1A | |
| SCHEMBL29358400 | 0.84 | TERT (0.49) | TERTHEXAHEXBSTAT3HIF1A | |
| Hydrochloric Acid SCHEMBL9623271 | 0.83 | TERT (0.45) | TERTHEXAHEXBSTAT3HIF1A | |
| SCHEMBL9622936 | 0.82 | TERT (0.52) | TERTHEXAHEXBSTAT3HIF1A | |
| SCHEMBL9623034 | 0.82 | TERT (0.47) | TERTHEXAHEXBWEE1CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166204-A | ISOINDOLE DERIVATIVES AND SALTS THEREOF AND ANTITUMOR AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1992-11-24 | — | — | US | disclosed |