Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 2/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HTR6 | P50406 | 4/20 | 0.45 |
| ▸ | HTR1A | P08908 | 3/20 | 0.45 |
| ▸ | HTR1D | P28221 | 3/20 | 0.45 |
| ▸ | HTR7 | P34969 | 3/20 | 0.45 |
| ▸ | HTR5A | P47898 | 3/20 | 0.45 |
| ▸ | HTR1E | P28566 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MYLK | Q15746 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29351752 | 0.87 | TERT (0.47) | TERTPLK1HTR6ALDH1A1TDP1 | |
| SCHEMBL9623078 | 0.87 | TERT (0.47) | TERTPLK1HTR6ALDH1A1TDP1 | |
| SCHEMBL9622455 | 0.87 | MEN1 (0.46) | MEN1KMT2AMAPTALDH1A1APEX1 | |
| SCHEMBL9622882 | 0.87 | MEN1 (0.48) | MEN1KMT2AMAPTALDH1A1APEX1 | |
| SCHEMBL29386554 | 0.85 | PDGFRB (0.48) | TERTMEN1KMT2AHTR6HTR1A | |
| SCHEMBL9622438 | 0.84 | TERT (0.49) | TERTPLK1MEN1KMT2AHTR6 | |
| SCHEMBL9623021 | 0.84 | WEE1 (0.51) | TERTMEN1KMT2AMYLKTDP1 | |
| SCHEMBL29358400 | 0.84 | TERT (0.49) | TERTPLK1MEN1KMT2AHTR6 | |
| Hydrochloric Acid SCHEMBL9623357 | 0.83 | WEE1 (0.50) | TERTMEN1KMT2AMYLKTDP1 | |
| SCHEMBL9623119 | 0.83 | MYLK (0.47) | TERTPLK1MEN1KMT2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166204-A | ISOINDOLE DERIVATIVES AND SALTS THEREOF AND ANTITUMOR AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1992-11-24 | — | — | US | disclosed |