Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.69 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.61 |
| ▸ | PPARG | P37231 | 7/20 | 0.61 |
| ▸ | PPARD | Q03181 | 7/20 | 0.61 |
| ▸ | PPARA | Q07869 | 7/20 | 0.61 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.61 |
| ▸ | TSHR | P16473 | 4/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | TLR2 | O60603 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | FABP4 | P15090 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.61 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | ESR1 | P03372 | 1/20 | 0.61 |
| ▸ | PDE4A | P27815 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5545406 | 0.96 | ALOX5 (0.69) | ALOX5GPR84PPARGPPARDPPARA | |
| SCHEMBL126631 | 0.96 | ALOX5 (0.69) | ALOX5GPR84PPARGPPARDPPARA | |
| SCHEMBL9513062 | 0.96 | ALOX5 (0.69) | ALOX5GPR84PPARGPPARDPPARA | |
| SCHEMBL862219 | 0.96 | ALOX5 (0.69) | ALOX5GPR84PPARGPPARDPPARA | |
| SCHEMBL21941814 | 0.96 | ALOX5 (0.69) | ALOX5GPR84PPARGPPARDPPARA | |
| SCHEMBL10580840 | 0.96 | ALOX5 (0.69) | ALOX5GPR84PPARGPPARDPPARA | |
| Hydrogen Sulfide SCHEMBL27802019 | 0.95 | ALOX5 (0.67) | ALOX5GPR84PPARGPPARDPPARA | |
| Hydrochloric Acid SCHEMBL11739322 | 0.95 | ALOX5 (0.67) | ALOX5GPR84PPARGPPARDPPARA | |
| Charcoal, Activated SCHEMBL5436853 | 0.95 | ALOX5 (0.67) | ALOX5GPR84PPARGPPARDPPARA | |
| SCHEMBL11239681 | 0.93 | ALOX5 (0.64) | ALOX5GPR84PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0319576-B1 | PROSTAGLANDIN DERIVATIVES, PROCESSES FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES | IBI- Istituto Biochimico Italiano Giovanni Lorenzini S.p.A. (IT) | 1992-01-08 | — | — | EP | disclosed |
| EP-0319576-A1 | PROSTAGLANDIN DERIVATIVES, PROCESSES FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES. | ISTITUTO BIOCHIMICO ITALIANO (IT) | 1989-06-14 | — | — | EP | disclosed |
| WO-1988010252-A1 | PROSTAGLANDIN DERIVATES, THEIR PROCESS AND PHARMACEUTICAL COMPOSITIONS | IBI ISTITUTO BIOCHIMICO ITALIANO GIOVANNI LORENZIN (IT) | 1988-12-29 | — | — | WO | disclosed |