Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.69 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.61 |
| ▸ | PPARG | P37231 | 7/20 | 0.61 |
| ▸ | PPARD | Q03181 | 7/20 | 0.61 |
| ▸ | PPARA | Q07869 | 7/20 | 0.61 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.61 |
| ▸ | TSHR | P16473 | 4/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | TLR2 | O60603 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | FABP4 | P15090 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.61 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | ESR1 | P03372 | 1/20 | 0.61 |
| ▸ | PDE4A | P27815 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10580840 | 1.00 | ALOX5 (0.69) | ALOX5GPR84PPARGPPARDPPARA | |
| SCHEMBL9513062 | 1.00 | ALOX5 (0.69) | ALOX5GPR84PPARGPPARDPPARA | |
| SCHEMBL126631 | 1.00 | ALOX5 (0.69) | ALOX5GPR84PPARGPPARDPPARA | |
| SCHEMBL862219 | 1.00 | ALOX5 (0.69) | ALOX5GPR84PPARGPPARDPPARA | |
| SCHEMBL21941814 | 1.00 | ALOX5 (0.69) | ALOX5GPR84PPARGPPARDPPARA | |
| Hydrochloric Acid SCHEMBL11739322 | 0.98 | ALOX5 (0.67) | ALOX5GPR84PPARGPPARDPPARA | |
| Hydrogen Sulfide SCHEMBL27802019 | 0.98 | ALOX5 (0.67) | ALOX5GPR84PPARGPPARDPPARA | |
| Charcoal, Activated SCHEMBL5436853 | 0.98 | ALOX5 (0.67) | ALOX5GPR84PPARGPPARDPPARA | |
| SCHEMBL11239681 | 0.96 | ALOX5 (0.64) | ALOX5GPR84PPARGPPARDPPARA | |
| SCHEMBL9623339 | 0.96 | ALOX5 (0.69) | ALOX5GPR84PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9849122-B2 | Combination therapy | AERIE PHARMACEUTICALS, INC. (US) | 2017-12-26 | — | — | US | disclosed |
| US-9254326-B2 | Pharmaceutical composition comprising 11-deoxy-prostaglandin compound and method for stabilizing the compound | R-TECH UENO, LTD. (JP) | 2016-02-09 | — | — | US | disclosed |
| US-20150126609-A1 | PHARMACEUTICAL COMPOSITION COMPRISING 11-DEOXY -PROSTAGLANDIN COMPOUND AND METHOD FOR STABILIZING THE COMPOUND | SUCAMPO AG (CH) | 2015-05-07 | — | — | US | disclosed |
| US-8969324-B2 | Pharmaceutical composition comprising 11-deoxy-prostaglandin compound and method for stabilizing the compound | R-TECH UENO, LTD. (JP) | 2015-03-03 | — | — | US | disclosed |
| US-8962688-B2 | Method for the treatment of gastrointestinal disorders | SUCAMPO AG (CH) | 2015-02-24 | — | — | US | disclosed |
| US-20140315994-A1 | METHOD FOR TREATING GASTROINTESTINAL DISORDER | SUCAMPO AG (CH) | 2014-10-23 | — | — | US | disclosed |
| US-8569058-B2 | Nerve regeneration promoters | ONO PHARMACEUTICAL CO., LTD. (JP) | 2013-10-29 | — | — | US | disclosed |
| US-8569058-B2 | Nerve regeneration promoters | ONO PHARMACEUTICAL CO., LTD. (JP) | 2013-10-29 | — | — | US | disclosed |
| US-8513441-B2 | Prostaglandin synthesis and intermediates for use therein | ALPHORA RESEARCH INC. (CA) | 2013-08-20 | — | — | US | disclosed |
| US-20130072695-A1 | PROSTAGLANDIN SYNTHESIS AND INTERMEDIATES FOR USE THEREIN | ALPHORA RESEARCH INC. (CA) | 2013-03-21 | — | — | US | disclosed |
| US-3936487-A | RACEMIC MIXTURES, ANTIULCER, ANTICOAGULANT, LABOR INDUCING | THE UPJOHN COMPANY (US) | 1976-02-03 | — | — | US | disclosed |
| US-3933889-A | 4,5-Cis-didehydro-PGF1.sub.α analogs | THE UPJOHN COMPANY (US) | 1976-01-20 | — | — | US | disclosed |
| US-3933897-A | ANTIULCER, ASTHMA, RENAL DYSFUNCTION | THE UPJOHN COMPANY (US) | 1976-01-20 | — | — | US | disclosed |
| US-3933895-A | PROSTAGLANDINS, ANTIULCER, ANTICOAGULANTS, NASAL PATENCY, LABOR INDUCERS, WOUND HEALING | THE UPJOHN COMPANY (US) | 1976-01-20 | — | — | US | disclosed |
| US-3933900-A | ANTIULCER, ANTICOAGULANTS, NASAL PATENCY, LABOR INDUCERS, WOUND HEALING | THE UPJOHN COMPANY (US) | 1976-01-20 | — | — | US | disclosed |
| US-3933898-A | ANTIULCER, ANTICOAGULANTS, NASAL PATENCY, LABOR INDUCERS, WOUND HEALING | THE UPJOHN COMPANY (US) | 1976-01-20 | — | — | US | disclosed |
| US-3933896-A | ANTICOAGULANTS, ASTHMA, LABOR INDUCERS, CERVICAL DILATION | THE UPJOHN COMPANY (US) | 1976-01-20 | — | — | US | disclosed |
| US-3933899-A | ANTIULCER, ANTICOAGULANTS, NASAL PATENCY, LABOR INDUCERS, WOUND HEALING | THE UPJOHN COMPANY (US) | 1976-01-20 | — | — | US | disclosed |
| US-3931279-A | 5-Oxa prostaglandin F2.sub.α analogs | THE UPJOHN COMPANY (US) | 1976-01-06 | — | — | US | disclosed |
| US-3931289-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130072695-A1 | PROSTAGLANDIN SYNTHESIS AND INTERMEDIATES FOR USE THEREIN | ALOX5, PTGES, PTGIS | ALOX5 1/4885GPR84 1152/4885PPARG 328/4885 |
| US-20150126609-A1 | PHARMACEUTICAL COMPOSITION COMPRISING 11-DEOXY -PROSTAGLANDIN COMPOUND AND METHOD FOR STABILIZING THE COMPOUND | PTGER1, PTGES, PTGIS | ALOX5 12/4885GPR84 2271/4885PPARG 54/4885 |
| US-20140315994-A1 | METHOD FOR TREATING GASTROINTESTINAL DISORDER | SLC10A2, FABP6, FABP2 | ALOX5 16/4885GPR84 1408/4885PPARG 327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.