SCHEMBL9623381

SCHEMBL9623381

Oc1ccc(Oc2ccc(O)c(Cl)c2Cl)cc1

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
ESR1 P03372 1/20 0.50
ESR2 Q92731 1/20 0.50
LTA4H P09960 3/20 0.43
NR1H2 P55055 1/20 0.43
BAX Q07812 1/20 0.43
MAPK1 P28482 2/20 0.41
CYP3A4 P08684 1/20 0.41
TAAR5 O14804 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
PARP10 Q53GL7 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5180281 0.84 TTR (0.49) MEN1KMT2ALTA4HNR1H2BAX
SCHEMBL11159594 0.78 PDE7A (0.51) MEN1KMT2AMAPK1
SCHEMBL11402635 0.74 MEN1 (0.48) MEN1KMT2AESR1ESR2LTA4H
SCHEMBL11157607 0.74 THRA (0.49) MEN1KMT2A
SCHEMBL9623553 0.73 MEN1 (0.52) MEN1KMT2AESR1ESR2LTA4H
SCHEMBL676467 0.72 MEN1 (0.56) MEN1KMT2AESR1ESR2LTA4H
SCHEMBL2711865 0.72 MEN1 (0.56) MEN1KMT2AESR1ESR2LTA4H
SCHEMBL14645135 0.72 MEN1 (0.50) MEN1KMT2AESR1ESR2LTA4H
SCHEMBL5700724 0.72 ESR1 (0.50) MEN1KMT2AESR1ESR2LTA4H
SCHEMBL11307521 0.72 MEN1 (0.50) MEN1KMT2AESR1ESR2LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0212944-B1 MELT-PROCESSABLE AROMATIC COPOLYESTER Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1992-04-08 EP disclosed
US-4746721-A ENGINEERING PLASTICS KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1988-05-24 US disclosed
EP-0212944-A2 Melt-processable aromatic copolyester Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1987-03-04 EP disclosed
US-4306094-A FROM HYDROQUINONES IN THE PRESENCE OF CATION EXCHANGE RESINS E. I. DU PONT DE NEMOURS & CO. (US) 1981-12-15 US disclosed