Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.55 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.54 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.54 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9623398 | 1.00 | LOXL2 (0.55) | LOXL2CYP4F2CYP4A11SLC7A5ABHD6 | |
| SCHEMBL9442216 | 0.83 | LOXL2 (0.50) | LOXL2CYP4F2CYP4A11MEN1NPC1 | |
| SCHEMBL9442219 | 0.83 | LOXL2 (0.50) | LOXL2CYP4F2CYP4A11MEN1NPC1 | |
| SCHEMBL4682498 | 0.81 | LOXL2 (0.67) | LOXL2CYP4F2CYP4A11SLC7A5ABHD6 | |
| SCHEMBL697890 | 0.79 | LOXL2 (0.68) | LOXL2CYP4F2CYP4A11SLC7A5ABHD6 | |
| SCHEMBL13601337 | 0.79 | LOXL2 (0.59) | LOXL2CYP4F2CYP4A11SLC7A5ABHD6 | |
| SCHEMBL757447 | 0.77 | LOXL2 (0.64) | LOXL2CYP4F2CYP4A11SLC7A5ABHD6 | |
| SCHEMBL8367820 | 0.74 | LOXL2 (0.60) | LOXL2CYP4F2CYP4A11SLC7A5FOLH1 | |
| SCHEMBL126284 | 0.74 | LOXL2 (0.74) | LOXL2CYP4F2CYP4A11SLC7A5FOLH1 | |
| SCHEMBL70173 | 0.74 | CYP4F2 (0.83) | LOXL2CYP4F2CYP4A11SLC7A5FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0235452-B1 | ORGANIC COMPOUNDS AND THEIR PHARMACEUTICAL USE | LILLY INDUSTRIES LIMITED (GB) | 1992-03-18 | — | — | EP | disclosed |
| US-4845110-A | Organic compounds and their pharmaceutical use | LILLY INDUSTRIES LIMITED (GB) | 1989-07-04 | — | — | US | disclosed |
| EP-0235452-A2 | Organic compounds and their pharmaceutical use | LILLY INDUSTRIES LIMITED (GB) | 1987-09-09 | — | — | EP | disclosed |