Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | FABP7 | O15540 | 4/20 | 0.43 |
| ▸ | FABP3 | P05413 | 4/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 4/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1336291 | 0.89 | ALDH1A1 (0.57) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL6836791 | 0.89 | ALDH1A1 (0.57) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL27615000 | 0.86 | ALDH1A1 (0.54) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL23795398 | 0.83 | ALDH1A1 (0.51) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL27457567 | 0.83 | ALDH1A1 (0.51) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL1358200 | 0.83 | ALDH1A1 (0.62) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL7181428 | 0.82 | ALDH1A1 (0.65) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL67480 | 0.81 | ALDH1A1 (0.60) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL29373404 | 0.81 | ALDH1A1 (0.60) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL28989629 | 0.80 | ALDH1A1 (0.48) | ALDH1A1HSD17B10GAAPGRPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0184800-B1 | OXYGEN PERMEABLE SOFT CONTACT LENS MATERIAL | Toyo Contact Lens Co., Ltd. (JP) | 1992-04-29 | — | — | EP | disclosed |
| US-4826936-A | Silicone-containing contact lens material and contact lenses made thereof | POLYMER TECHNOLOGY CORP. (US) | 1989-05-02 | — | — | US | disclosed |
| US-4649184-A | UNSATURATED POLYSILOXANE COPOLYMER WITH MONOMER HAVING SIYLATED HYDROXYL GROUPS | TOYO CONTACT LENS CO., LTD. (JP) | 1987-03-10 | — | — | US | disclosed |
| US-4625007-A | Silicone-containing contact lens material and contact lenses made thereof | POLYMER TECHNOLOGY CORPORATION (US) | 1986-11-25 | — | — | US | disclosed |
| US-4604479-A | Silicone-containing contact lens material and contact lenses made thereof | POLYMER TECHNOLOGY CORPORATION (US) | 1986-08-05 | — | — | US | disclosed |
| EP-0184800-A2 | Oxygen permeable soft contact lens material | Toyo Contact Lens Co., Ltd. (JP) | 1986-06-18 | — | — | EP | disclosed |
| US-4463149-A | UNSATURATED POLYSILOXANES | POLYMER TECHNOLOGY CORPORATION (US) | 1984-07-31 | — | — | US | disclosed |
| US-4424328-A | POLYMERS OF UNSATURATED MULTIFUNCTIONAL POLYSILOXANES | POLYMER TECHNOLOGY CORPORATION (US) | 1984-01-03 | — | — | US | disclosed |