Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Mequinol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.59 |
| ▸ | LTA4H | P09960 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | APP | P05067 | 2/20 | 0.53 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.51 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.51 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.51 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.51 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 3/20 | 0.50 |
| ▸ | BCR | P11274 | 3/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.50 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,3-Dimethoxybenzene SCHEMBL7736576 | 0.91 | LTA4H (0.64) | ESR2LTA4HAPPENPP2MEN1 | |
| 1-Hydroxy-3-Methoxybenzene SCHEMBL29421717 | 0.91 | — | — | |
| 1-Hydroxy-3-Methoxybenzene SCHEMBL28256 | 0.91 | — | — | |
| 1-Hydroxy-3-Methoxybenzene SCHEMBL9623569 | 0.89 | ESR1 (0.59) | ESR2ESR1ENPP2MEN1KMT2A | |
| 1-Hydroxy-3-Methoxybenzene SCHEMBL27446904 | 0.89 | ESR1 (0.62) | ESR2ESR1ENPP2MEN1KMT2A | |
| 1-Hydroxy-3-Methoxybenzene SCHEMBL27770537 | 0.89 | ESR1 (0.62) | ESR2ESR1ENPP2MEN1KMT2A | |
| 1-Hydroxy-3-Methoxybenzene SCHEMBL6760019 | 0.89 | ESR1 (0.62) | ESR2ESR1ENPP2MEN1KMT2A | |
| 1-Hydroxy-3-Methoxybenzene SCHEMBL7390774 | 0.89 | ESR1 (0.62) | ESR2ESR1ENPP2MEN1KMT2A | |
| 1-Hydroxy-3-Methoxybenzene SCHEMBL28322080 | 0.89 | ESR1 (0.62) | ESR2ESR1ENPP2MEN1KMT2A | |
| 1-Hydroxy-3-Methoxybenzene SCHEMBL11366244 | 0.87 | ESR1 (0.61) | ESR2ESR1ENPP2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087260-A1 | PHOTOSENSITIVE RESIN COMPOSITION | CLARIANT INTERNATIONAL LTD. (CH) | 2001-03-28 | — | — | EP | disclosed |