Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 11/20 | 0.60 |
| ▸ | TSHR | P16473 | 9/20 | 0.60 |
| ▸ | HPGD | P15428 | 9/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | RECQL | P46063 | 3/20 | 0.50 |
| ▸ | TTR | P02766 | 3/20 | 0.50 |
| ▸ | CASP1 | P29466 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL68191 | 0.80 | HSD17B10 (0.77) | HSD17B10TSHRHPGDMAPK1CYP3A4 | |
| SCHEMBL14957739 | 0.77 | TSHR (0.46) | HSD17B10TSHRHPGDMAPK1CYP3A4 | |
| SCHEMBL9623558 | 0.76 | AKR1C2 (0.47) | HSD17B10TSHRHPGDMAPK1ALDH1A1 | |
| SCHEMBL29364629 | 0.75 | HSD17B10 (1.00) | HSD17B10TSHRHPGDMAPK1CYP3A4 | |
| SCHEMBL54380 | 0.75 | HSD17B10 (1.00) | HSD17B10TSHRHPGDMAPK1CYP3A4 | |
| SCHEMBL11293469 | 0.73 | CYP2A6 (0.50) | HSD17B10TSHRHPGDMAPK1CYP3A4 | |
| SCHEMBL11879785 | 0.73 | HSD17B10 (0.57) | HSD17B10TSHRHPGDMAPK1CYP3A4 | |
| SCHEMBL5948553 | 0.73 | HSD17B10 (0.65) | HSD17B10TSHRHPGDMAPK1CYP3A4 | |
| SCHEMBL70606 | 0.73 | HSD17B10 (0.65) | HSD17B10TSHRHPGDMAPK1CYP3A4 | |
| SCHEMBL9623548 | 0.71 | ESR1 (0.44) | HSD17B10TSHRHPGDMAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0212944-B1 | MELT-PROCESSABLE AROMATIC COPOLYESTER | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1992-04-08 | — | — | EP | disclosed |
| US-4746721-A | ENGINEERING PLASTICS | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1988-05-24 | — | — | US | disclosed |
| EP-0212944-A2 | Melt-processable aromatic copolyester | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1987-03-04 | — | — | EP | disclosed |