Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | CLK3 | P49761 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9625192 | 0.97 | SMN1; SMN2 (0.37) | SMN1; SMN2NPC1RAB9ABCHECLK1 | |
| SCHEMBL9624250 | 0.95 | BCHE (0.37) | SMN1; SMN2NPC1RAB9ABCHECLK1 | |
| SCHEMBL9623769 | 0.88 | SMN1; SMN2 (0.39) | SMN1; SMN2NPC1RAB9ACLK1CLK2 | |
| SCHEMBL9624675 | 0.87 | SMN1; SMN2 (0.38) | SMN1; SMN2NPC1RAB9ACLK1CLK2 | |
| SCHEMBL9624779 | 0.87 | LMNA (0.39) | SMN1; SMN2ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL9624353 | 0.85 | SMN1; SMN2 (0.39) | SMN1; SMN2NPC1RAB9ACLK1CLK2 | |
| SCHEMBL9624617 | 0.84 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9624961 | 0.84 | LMNA (0.39) | SMN1; SMN2ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL9624619 | 0.83 | SMN1; SMN2 (0.37) | SMN1; SMN2NPC1RAB9ABCHECLK1 | |
| SCHEMBL9625079 | 0.82 | LMNA (0.39) | SMN1; SMN2ALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116986-A | HETEROAROMATIC AMINE DERIVATIVES | DR. KARL THOMAE GMBH (DE) | 1992-05-26 | — | — | US | disclosed |
| US-4912115-A | Cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1990-03-27 | — | — | US | disclosed |