Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 5/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.67 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.67 |
| ▸ | RELA | Q04206 | 2/20 | 0.67 |
| ▸ | FNTA | P49354 | 1/20 | 0.62 |
| ▸ | FNTB | P49356 | 1/20 | 0.62 |
| ▸ | PGR | P06401 | 3/20 | 0.41 |
| ▸ | AR | P10275 | 3/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10629868 | 0.90 | NFKB1 (0.67) | NFKB1KCNH2NFKB2RELAFNTA | |
| SCHEMBL8755264 | 0.90 | NFKB1 (0.67) | NFKB1KCNH2NFKB2RELAFNTA | |
| SCHEMBL10629876 | 0.90 | NFKB1 (0.67) | NFKB1KCNH2NFKB2RELAFNTA | |
| SCHEMBL10497021 | 0.83 | NFKB1 (0.80) | NFKB1KCNH2NFKB2RELAFNTA | |
| SCHEMBL9623669 | 0.82 | NFKB1 (0.56) | NFKB1KCNH2NFKB2RELAFNTA | |
| SCHEMBL10766204 | 0.82 | NFKB1 (0.69) | NFKB1KCNH2NFKB2RELAFNTA | |
| SCHEMBL10766209 | 0.82 | NFKB1 (0.69) | NFKB1KCNH2NFKB2RELAFNTA | |
| SCHEMBL9069866 | 0.81 | NFKB1 (0.87) | NFKB1KCNH2NFKB2RELAFNTA | |
| SCHEMBL9069865 | 0.81 | NFKB1 (0.87) | NFKB1KCNH2NFKB2RELAFNTA | |
| SCHEMBL18351261 | 0.80 | NFKB1 (0.86) | NFKB1KCNH2NFKB2RELAFNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268400-B1 | STEROIDAL 17ALPHA-SILYL ETHERS AND PROCESS TO CORTICOIDS AND PROGESTERONES | THE UPJOHN COMPANY (US) | 1992-04-29 | — | — | EP | claimed |