Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9623546 | 0.92 | NR3C1 (0.34) | NR3C1 | |
| SCHEMBL9623715 | 0.89 | NR3C1 (0.32) | NR3C1 | |
| SCHEMBL10528693 | 0.88 | NR3C1 (0.31) | NR3C1 | |
| SCHEMBL9623719 | 0.84 | NR3C1 (0.32) | NR3C1 | |
| SCHEMBL9623691 | 0.79 | NR3C1 (0.39) | NR3C1 | |
| SCHEMBL9623923 | 0.78 | SRD5A2 (0.37) | — | |
| SCHEMBL9623391 | 0.78 | POLB (0.35) | — | |
| SCHEMBL8235811 | 0.77 | NR3C1 (0.39) | NR3C1 | |
| SCHEMBL14308861 | 0.77 | NR3C1 (0.39) | NR3C1 | |
| SCHEMBL14284894 | 0.77 | NR3C1 (0.39) | NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268400-B1 | STEROIDAL 17ALPHA-SILYL ETHERS AND PROCESS TO CORTICOIDS AND PROGESTERONES | THE UPJOHN COMPANY (US) | 1992-04-29 | — | — | EP | claimed |
| US-4977255-A | Steroidal 17α-silyl ethers and process to corticoids and progesterones | THE UPJOHN COMPANY (US) | 1990-12-11 | — | — | US | claimed |
| EP-0334875-A1 | STEROIDAL 17$g(a)-SILYL ETHERS AND PROCESS TO CORTICOIDS AND PROGGESTERONES | THE UPJOHN COMPANY (US) | 1989-10-04 | — | — | EP | claimed |
| EP-0268400-A1 | Steroidal 17alpha-silyl ethers and process to corticoids and progesterones | THE UPJOHN COMPANY (US) | 1988-05-25 | — | — | EP | claimed |
| WO-1988003534-A1 | STEROIDAL 17alpha-SILYL ETHERS AND PROCESS TO CORTICOIDS AND PROGGESTERONES | THE UPJOHN COMPANY (US) | 1988-05-19 | — | — | WO | claimed |