Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 6/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SHBG | P04278 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | PGR | P06401 | 3/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9623540 | 1.00 | NR3C1 (0.39) | NR3C1CYP19A1LMNAHIF1AMEN1 | |
| SCHEMBL9623073 | 0.91 | NR3C1 (0.39) | NR3C1CYP19A1ARPGRNR3C2 | |
| SCHEMBL9623172 | 0.86 | NR3C1 (0.53) | NR3C1CYP19A1SHBGARPGR | |
| SCHEMBL9241562 | 0.86 | NR3C1 (0.53) | NR3C1CYP19A1SHBGARPGR | |
| SCHEMBL9623677 | 0.85 | NFKB1 (0.37) | NR3C1CYP19A1LMNAHIF1AAR | |
| SCHEMBL9623135 | 0.84 | CYP17A1 (0.40) | NR3C1CYP19A1ARPGRNR3C2 | |
| SCHEMBL9623473 | 0.80 | CYP19A1 (0.37) | NR3C1CYP19A1LMNAHIF1AMEN1 | |
| SCHEMBL9624281 | 0.79 | NR3C1 (0.43) | NR3C1CYP19A1LMNAHIF1AMEN1 | |
| SCHEMBL9623638 | 0.77 | NR3C1 (0.53) | NR3C1CYP19A1SHBGARPGR | |
| SCHEMBL9623126 | 0.77 | NFKB1 (0.48) | NR3C1CYP19A1LMNAHIF1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268400-B1 | STEROIDAL 17ALPHA-SILYL ETHERS AND PROCESS TO CORTICOIDS AND PROGESTERONES | THE UPJOHN COMPANY (US) | 1992-04-29 | — | — | EP | claimed |