Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 12/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.36 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8580626 | 1.00 | ACE (0.42) | ACEFOLH1NAALAD2ALDH1A1 | |
| SCHEMBL12308077 | 0.85 | ALDH1A1 (0.53) | ACEFOLH1NAALAD2ALDH1A1 | |
| SCHEMBL15432520 | 0.82 | ACE (0.46) | ACEFOLH1NAALAD2ALDH1A1 | |
| SCHEMBL8416407 | 0.82 | ACE (0.46) | ACEFOLH1NAALAD2ALDH1A1 | |
| SCHEMBL8419719 | 0.82 | ACE (0.46) | ACEFOLH1NAALAD2ALDH1A1 | |
| SCHEMBL8416400 | 0.82 | ACE (0.46) | ACEFOLH1NAALAD2ALDH1A1 | |
| SCHEMBL20287636 | 0.81 | ACE (0.44) | ACEALDH1A1 | |
| SCHEMBL12989759 | 0.79 | ACE (0.48) | ACE | |
| SCHEMBL20122457 | 0.78 | ACE (0.46) | ACEFOLH1 | |
| SCHEMBL5967595 | 0.78 | ZDHHC7 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0472634-A1 | PROCESS FOR THE N-MONOACYLATION OF CYSTEINE | AKTIEBOLAGET ASTRA (SE) | 1992-03-04 | — | — | EP | disclosed |
| WO-1990014335-A1 | PROCESS FOR THE N-MONOACYLATION OF CYSTEINE | AKTIEBOLAGET ASTRA (SE) | 1990-11-29 | — | — | WO | disclosed |