Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 10/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.39 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8419719 | 1.00 | ACE (0.46) | ACEITGB1ITGA4FOLH1NAALAD2 | |
| SCHEMBL8416407 | 1.00 | ACE (0.46) | ACEITGB1ITGA4FOLH1NAALAD2 | |
| SCHEMBL8417794 | 0.93 | ALDH1A1 (0.52) | ACEITGB1ITGA4ALDH1A1 | |
| SCHEMBL15432520 | 0.88 | ACE (0.46) | ACEFOLH1NAALAD2ALDH1A1 | |
| SCHEMBL30830405 | 0.84 | NOD1 (0.48) | ACEITGB1ITGA4FOLH1NAALAD2 | |
| SCHEMBL2545697 | 0.84 | NOD1 (0.48) | ACEITGB1ITGA4FOLH1NAALAD2 | |
| SCHEMBL2545708 | 0.84 | NOD1 (0.48) | ACEITGB1ITGA4FOLH1NAALAD2 | |
| SCHEMBL12989759 | 0.84 | ACE (0.48) | ACE | |
| SCHEMBL9623845 | 0.82 | ACE (0.42) | ACEFOLH1NAALAD2ALDH1A1 | |
| SCHEMBL20287636 | 0.82 | ACE (0.44) | ACEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889050-A | IMMUNOMODULATOR | ASTRA AKTIEBOLAG (SE) | 1999-03-30 | — | — | US | disclosed |
| EP-0463514-B1 | 3.3'-Dithiobis (propionic acids) and esters thereof | ASTRA AB (SE) | 1995-04-05 | — | — | EP | disclosed |
| EP-0463514-A1 | 3.3'-Dithiobis (propionic acids) and esters thereof | Astra Aktiebolag (SE) | 1992-01-02 | — | — | EP | disclosed |