Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.51 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.51 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9161049 | 0.94 | MAPT (0.53) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL9623693 | 0.92 | MEN1 (0.52) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL934307 | 0.81 | MAPT (0.70) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL11466494 | 0.81 | SMN1; SMN2 (0.57) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL29799957 | 0.81 | MAPT (0.70) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL9168342 | 0.80 | MAPT (0.50) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL9623861 | 0.80 | TDP1 (0.49) | MAPTMEN1KMT2AALDH1A1PTPN1 | |
| SCHEMBL9623272 | 0.79 | MAPT (0.50) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL498265 | 0.78 | ALDH1A1 (0.69) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL9170930 | 0.77 | MAPT (0.61) | MAPTMEN1KMT2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350386-B1 | UNSATURATED DERIVATIVES OF LIPID SOLUBLE BENZAL MALONATES, AND THEIR USE AS UV ABSORBERS IN THE COSMETIC FIELD | L'OREAL (FR) | 1992-04-08 | — | — | EP | claimed |