SCHEMBL9623693

SCHEMBL9623693

C=CCc1cc(C=C(C(=O)OCC)C(=O)OCC)ccc1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.52
KMT2A Q03164 6/20 0.52
MAPT P10636 7/20 0.52
LMNA P02545 4/20 0.52
NPSR1 Q6W5P4 2/20 0.52
MAPK1 P28482 2/20 0.52
CYP1A2 P05177 1/20 0.52
CYP2C9 P11712 1/20 0.52
CYP2C19 P33261 1/20 0.52
S1PR4 O95977 1/20 0.52
S1PR1 P21453 1/20 0.52
POLB P06746 2/20 0.46
PLIN1 O60240 1/20 0.46
PLIN5 Q00G26 1/20 0.46
ABHD5 Q8WTS1 1/20 0.46
GABRA1 P14867 2/20 0.45
GABRB2 P47870 2/20 0.45
ALDH1A1 P00352 2/20 0.44
GLO1 Q04760 1/20 0.44
NR1H4 Q96RI1 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9623907 0.92 MAPT (0.51) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL9161049 0.85 MAPT (0.53) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL9515452 0.82 MEN1 (0.63) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL27884554 0.81 GLO1 (0.55) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL8520763 0.80 GABRA1 (0.53) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL9623288 0.79 MEN1 (0.64) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL14253554 0.79 TTR (0.68) TTRDPP4
SCHEMBL14381935 0.77 TTR (0.48) POLBGABRA1GABRB2KDM4ETTR
SCHEMBL9168342 0.77 MAPT (0.50) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL29799957 0.77 MAPT (0.70) MEN1KMT2AMAPTLMNANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5175340-A Sunscreen agents, stabilizers L'OREAL (FR) 1992-12-29 US claimed
EP-0350386-B1 UNSATURATED DERIVATIVES OF LIPID SOLUBLE BENZAL MALONATES, AND THEIR USE AS UV ABSORBERS IN THE COSMETIC FIELD L'OREAL (FR) 1992-04-08 EP claimed
JP-2059541-A None JP disclosed
US-5175340-A Sunscreen agents, stabilizers L'OREAL (FR) 1992-12-29 US disclosed
JP-H0259541-A ULTRAVIOLET RADIATION ABSORBER L'OREAL SA 1990-02-28 JP disclosed